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    The novel orally active guanylhydrazone CPSI-2364 prevents postoperative ileus in mice independently of anti-inflammatory vagus nerve signaling

    Postoperative ileus (POI) is an iatrogenic complication of abdominal surgery, mediated by a severe inflammation of the muscularis externa (ME). Previously, we demonstrated that intravenous application of the t...

    S. Wehner, T. O. Vilz, N. Sommer, T. Sielecki… in Langenbeck's Archives of Surgery (2012)