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  1. Article

    Open Access

    Pharmacodynamic evaluation and safety assessment of treatment with antibodies to serum amyloid P component in patients with cardiac amyloidosis: an open-label Phase 2 study and an adjunctive immuno-PET imaging study

    In a Phase I study treatment with the serum amyloid P component (SAP) depleter miridesap followed by monoclonal antibody to SAP (dezamizumab) showed removal of amyloid from liver, spleen and kidney in patients...

    Ashutosh Wechalekar, Gunnar Antoni, Wasfi Al Azzam in BMC Cardiovascular Disorders (2022)

  2. No Access

    Article

    Immunotherapeutic strategies in kidney cancer—when TKIs are not enough

    The management of metastatic clear-cell renal-cell carcinoma has been revolutionized by the approval of targeted therapies. These targeted therapies have, however, been unable to provide robust complete respon...

    Swethajit Biswas, Tim Eisen in Nature Reviews Clinical Oncology (2009)