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Open AccessCorrection: Undernutrition in young children with congenital heart disease undergoing cardiac surgery in a low‑income environment
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Open AccessImpairment in sleep health in young adults with chronic pain: a modifiable risk factor
Impairments in sleep health are associated with the development or worsening of chronic pain. Further, chronic pain can cause sleep health disruption by impacting sleep onset, sleep maintenance, sleep quality,...
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Open AccessBoosting neuregulin 1 type-III expression hastens SMA motor axon maturation
Intercellular communication between axons and Schwann cells is critical for attaining the complex morphological steps necessary for axon maturation. In the early onset motor neuron disease spinal muscular atro...
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Open AccessImproved constraints on effective top quark interactions using edge convolution networks
We explore the potential of Graph Neural Networks (GNNs) to improve the performance of high-dimensional effective field theory parameter fits to collider data beyond traditional rectangular cut-based different...
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Open AccessThe Rise and Fall of the Aid Effectiveness Norm
This article analyzes the rise and fall of the aid effectiveness norm, using the lens of Finnemore and Sikkink’s norm ‘life cycle’. I argue that, although donors and recipients endorsed the founding principles...
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Open AccessThe Use of Computer Simulation Modeling to Estimate Complications in Patients with Type 2 Diabetes Mellitus: Comparative Validation of the Cornerstone Diabetes Simulation Model
The objective of this study was to assess the validity of the Cornerstone Diabetes Simulation (CDS), a Microsoft Excel®-based patient-level simulation for type 2 diabetes mellitus based on risk equations from the...
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Open AccessComprehensive functional profiling of long non-coding RNAs through a novel pan-cancer integration approach and modular analysis of their protein-coding gene association networks
Long non-coding RNAs (lncRNAs) are emerging as crucial regulators of cellular processes in diseases such as cancer, although the functions of most remain poorly understood. To address this, here we apply a nov...
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Open AccessKinetic modeling of tumor regression incorporating the concept of cancer stem-like cells for patients with locally advanced lung cancer
Personalized medicine for patients receiving radiation therapy remains an elusive goal due, in part, to the limits in our understanding of the underlying mechanisms governing tumor response to radiation. The p...
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Open AccessThe Hiperwall tiled-display wall system for Big-Data research
In the era of Big Data, with the increasing use of large-scale data-driven applications, visualization of very large high-resolution images and extracting useful information (searching for specific targets or ...
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Open AccessACTA2 mutation and postpartum hemorrhage: a case report
ACTA2 encodes smooth muscle specific α-actin, a critical component or the contractile complex of vascular smooth muscle. Mutations in ACTA2 are the most common genetic cause of thoraci...
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Open AccessRe-examining the ECB’s two-pillar monetary policy strategy: Are there any deviations during and the pre-financial crisis periods?
This paper addresses the extent to which the ECB rate setting responded to inflation and monetary growth in the run up to, and during, the financial crisis of the late 2000s. The analysis covers the period bet...
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Open AccessShaped by asymmetrical interdependence: a qualitative case study of the external influences on international non-governmental organizations´ implementation of equity principles in HIV/AIDS work
Addressing inequities is a key role for international non-governmental organizations (INGOs) working in health and development. Yet, putting equity principles into practice can prove challenging. In-depth empi...
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Open AccessA Microsoft-Excel-based tool for running and critically appraising network meta-analyses—an overview and application of NetMetaXL
The use of network meta-analysis has increased dramatically in recent years. WinBUGS, a freely available Bayesian software package, has been the most widely used software package to conduct network meta-analys...
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Open AccessNGX-4010, a capsaicin 8% patch, for the treatment of painful HIV-associated distal sensory polyneuropathy: integrated analysis of two phase III, randomized, controlled trials
HIV-associated distal sensory polyneuropathy (HIV-DSP) is the most frequently reported neurologic complication associated with HIV infection. NGX-4010 is a capsaicin 8% dermal patch with demonstrated efficacy ...
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Open AccessAdvances in genome-wide RNAi cellular screens: a case study using the Drosophila JAK/STAT pathway
Genome-scale RNA-interference (RNAi) screens are becoming ever more common gene discovery tools. However, whilst every screen identifies interacting genes, less attention has been given to how factors such as ...
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Open AccessRadiation-induced skin injury in the animal model of scleroderma: implications for post-radiotherapy fibrosis
Radiation therapy is generally contraindicated for cancer patients with collagen vascular diseases (CVD) such as scleroderma due to an increased risk of fibrosis. The tight skin (TSK) mouse has skin which, in ...
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Open AccessAuto-augmentation: ought it to be done?
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Open Access50th Annual Meeting of the Society for Research into Hydrocephalus and Spina Bifida
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Open Access49th Annual Meeting of the Society for Research into Hydrocephalus and Spina Bifida
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Anesthesia for Freeman-Sheldon syndrome using a laryngeal mask airway
To present a case of Freeman-Sheldon syndrome (FSS) with a previously unreported technique of anesthetic management, consisting of a malignant hyperthermia free anesthetic and laryngeal mask airway.