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  1. No Access

    Article

    Transferrin Is an Essential Factor for Myelination

    It has been established that oligodendrocytes, the myelin forming cells, participate in iron homeostasis through the synthesis and secretion of transferrin. Here we investigated whether a correlation exists be...

    A. Espinosa de los Monteros, S. Kumar, P. Zhao, C. J. Huang… in Neurochemical Research (1999)

  2. No Access

    Article

    Remyelination of the Adult Demyelinated Mouse Brain by Grafted Oligodendrocyte Progenitors and the Effect of B-104 Cografts

    The 4e transgenic mouse is characterized by overexpression of the PLP gene. Heterozygous littermates containing three PLP gene copies develop and myelinate normally. However, a progressive CNS demyelination be...

    A. Espinosa de los Monteros, H. Baba, P. M. Zhao, T. Pan… in Neurochemical Research (2001)

  3. No Access

    Article

    Down-Regulation of Platelet-Activating Factor Receptor Gene Expression During Focal Reversible Cerebral Ischemia in Rats

    Platelet-activating factor (PAF) is an endogenous potent phospholipid mediator in stroke and related to the post-ischemic brain damage. The aim of this study was to investigate the regulation and mechanisms of...

    **ong Zhang, **-Long Pan, **n-Tong Liu, Shuo Wang, Li-Juan Wang in Neurochemical Research (2007)

  4. No Access

    Article

    Effects of Phenylalanine and its Metabolites on Cytoplasmic Free Calcium in Cortical Neurons

    Classic phenylketonuria (PKU) is characterized by brain lesions. However, its underlying neurotoxic mechanisms remain unknown. Based on our previous studies, we hypothesized that calcium might participate in P...

    Y. G. Yu, F. G. Tang, J. Pan, X. F. Gu in Neurochemical Research (2007)

  5. No Access

    Article

    A Diffusion Barrier Between the Area Postrema and Nucleus Tractus Solitarius

    The blood–brain barrier (BBB) is a structural and functional barrier that prevents free exchange of circulating substances with the brain, where the endothelial cells of microvessels are joined by tight juncti...

    Qing-** Wang, Jian-Lian Guan, Weihong Pan, Abba J. Kastin… in Neurochemical Research (2008)

  6. No Access

    Article

    Cerebral Metabolic Changes in a Depression-like Rat Model of Chronic Forced Swimming Studied by Ex vivo High Resolution 1H Magnetic Resonance Spectroscopy

    Many previous in vivo 1H magnetic resonance spectroscopy (MRS) studies have shown that patients with major depressive disorder (MDD) are associated with perturbations of cerebral metabolism of neurotransmitters g...

    Chun-**a Li, Yaqiang Wang, Hongchang Gao, Wen-Ju Pan, Yun **ang… in Neurochemical Research (2008)

  7. No Access

    Article

    PMS777, a New Cholinesterase Inhibitor with Anti-Platelet Activated Factor Activity, Regulates Amyloid Precursor Protein Processing In Vitro

    Alzheimer’s disease (AD) is a neurodegenerative disorder characterized clinically by progressive impairment of memory and cognition. Previous data have shown that beta-amyloid (Aβ) cascade plays a central role...

    Hong-Qi Yang, Zhi-Kun Sun, Yan-**n Zhao, **g Pan, Mao-Wen Ba… in Neurochemical Research (2009)

  8. No Access

    Article

    Combination of G-CSF Administration and Human Amniotic Fluid Mesenchymal Stem Cell Transplantation Promotes Peripheral Nerve Regeneration

    Amniotic fluid mesenchymal stem cells (AFS) harbor the potential to improve peripheral nerve injury by inherited neurotrophic factor secretion, but present the drawback of the short-term survival after transpl...

    Hung-Chuan Pan, Chung-Jung Chen, Fu-Chou Cheng, Shu-Pen Ho… in Neurochemical Research (2009)

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    Article

    Lactacystin Stimulates Stellation of Cultured Rat Cortical Astrocytes

    Proteasome inhibition has been observed in many neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. Here, the effect of proteasome inhibition on the morphology of cultured rat corti...

    Qing-Guo Ren, Ying Yu, Deng-Ji Pan, **ang Luo, Xue-Zhen Wang… in Neurochemical Research (2009)

  10. No Access

    Article

    Human Amniotic Fluid Mesenchymal Stem Cells in Combination with Hyperbaric Oxygen Augment Peripheral Nerve Regeneration

    Purpose Attenuation of pro-inflammatory cytokines and associated inflammatory cell deposits rescues human amniotic fluid mesenchymal stem cells (AFS) from apoptosis. Hyperbaric oxygen (HBO) suppressed stimulus-in...

    Hung-Chuan Pan, Chun-Shih Chin, Dar-Yu Yang, Shu-Peng Ho… in Neurochemical Research (2009)

  11. No Access

    Article

    Nerve Growth Factor of Red Nucleus Involvement in Pain Induced by Spared Nerve Injury of the Rat Sciatic Nerve

    Nerve growth factor (NGF), a member of the neurotrophin family, is essential for the development and maintenance of sensory neurons and for the formation of central pain circuitry. The current study was design...

    Yuan-Yuan **g, Jun-Yang Wang, **ao-Li Li, Zhi-Hong Wang, Liu Pei… in Neurochemical Research (2009)

  12. No Access

    Article

    The Effects of a Cd81 Null Mutation on Retinal Pigment Epithelium in Mice

    The present study examines the effects of Cd81-null mutation on the development of the retinal pigment epithelium (RPE), specifically cell size and number of cells with multiple nuclei. The outlines of RPE in ret...

    Ye Pan, David F. Geisert, William E. Orr, Eldon E. Geisert in Neurochemical Research (2011)

  13. No Access

    Article

    Depletion of Nrf2 Enhances Inflammation Induced by Oxyhemoglobin in Cultured Mice Astrocytes

    Nuclear factor erythroid 2-related factor 2 (Nrf2)-antioxidant response element pathway has been proved to be the key regulator in reducing inflammatory damage, which is involved in subarachnoid hemorrhage (SA...

    Hao Pan, Handong Wang, Lin Zhu, Lei Mao, Liang Qiao, **ngfen Su in Neurochemical Research (2011)

  14. No Access

    Article

    Inhibition of Neuron-Specific CREB Dephosphorylation is Involved in Propofol and Ketamine-Induced Neuroprotection Against Cerebral Ischemic Injuries of Mice

    Propofol and ketamine may provide certain degree of neuroprotection, but the underlying mechanism remains unclear to date. The cAMP response element-binding protein (CREB) was proposed that its phosphorylation...

    Luowa Shu, Tianzuo Li, Song Han, Fang Ji, Chuxiong Pan… in Neurochemical Research (2012)

  15. No Access

    Article

    Necrostatin-1 Suppresses Autophagy and Apoptosis in Mice Traumatic Brain Injury Model

    Traumatic brain injury (TBI) results in neuronal apoptosis, autophagic cell death and necroptosis. Necroptosis is a newly discovered caspases-independent programmed necrosis pathway which can be triggered by a...

    Yao-Qi Wang, Long Wang, Ming-Yang Zhang, Tao Wang, Hai-Jun Bao… in Neurochemical Research (2012)

  16. No Access

    Article

    Evidence for Involvement of Uncoupling Proteins in Cerebral Mitochondrial Oxidative Phosphorylation Deficiency of Rats Exposed to 5,000 m High Altitude

    The present study aimed to investigate the change of proton leak and discuss the role of cerebral uncoupling proteins (UCPs) and its regulatory molecules non-esterified fatty acid (NEFA) in high altitude mitoc...

    Yu Xu, Yuliang Liu, Chen **a, Pan Gao, Jun-ze Liu in Neurochemical Research (2013)

  17. No Access

    Article

    Dynamic Change of Hydrogen Sulfide After Traumatic Brain Injury and its Effect in Mice

    Hydrogen sulfide (H2S) is a lipid-soluble, endogenously produced gaseous messenger molecule collectively known as gasotransmitter. Over the last several decades, gasotransmitters have emerged as potent cytoprotec...

    Mingyang Zhang, Haiyan Shan, Tao Wang, Weili Liu, Yaoqi Wang… in Neurochemical Research (2013)

  18. No Access

    Article

    Ulinastatin Alleviates Neuroinflammation but Fails to Improve Cognitive Function in Aged Rats Following Partial Hepatectomy

    Postoperative cognitive dysfunction (POCD) is very common complication of surgery in aged individuals. Accumulated evidence suggests that neuroinflammation may be the underlying cause of POCD. The aim of the p...

    Ma Li, Liu Yong-zhe, Ma Ya-qun, Zhang Sheng-suo, Zhang Li-tao… in Neurochemical Research (2013)

  19. No Access

    Article

    Glial Cells Activation Potentially Contributes to the Upregulation of Stromal Cell-Derived Factor-1α After Optic Nerve Crush in Rats

    Stromal cell-derived factor-1α (SDF-1α) plays an important role after injury. However, little is known regarding its temporal and spatial expression patterns or how it interacts with glial cells after optic ne...

    **-Tao Yang, Dong-Chao Pan, Er-Tao Chen, Yong-Yan Bi… in Neurochemical Research (2013)

  20. No Access

    Article

    Evaluation of Potential Antidepressant-Like Activity of Chalcone-1203 in Various Murine Experimental Depressant Models

    Two classic animal behavior despair tests-the forced swimming test (FST) and the tail suspension test (TST) were used to evaluate antidepressant-like activity of a new chalcone compound, chalcone-1203 in mice...

    Li-** Guan, Li-Ming Tang, Cheng-Yan Pan, Shui-Lian Zhao… in Neurochemical Research (2014)

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