-
Article
Open AccessThe value of CT shape quantification in predicting pathological classification of lung adenocarcinoma
To evaluate whether quantification of lung GGN shape is useful in predicting pathological categorization of lung adenocarcinoma and guiding the clinic.
-
Article
Open AccessMesenchymal stromal cell biotherapy for Parkinson’s disease premotor symptoms
Parkinson’s disease (PD) is a neurodegenerative disorder with motor deficits due to nigrostriatal dopamine depletion and with the non-motor/premotor symptoms (NMS) such as anxiety, cognitive dysfunction, depre...
-
Article
Open AccessEffects of morphological traits on body weight and analysis of growth-related genes of Parabramis pekinensis at different ages
Parabramis pekinensis was treated as research object in order to investigate the correlation between morphological traits and body weight. We measured 9 morphological indexes including total length (X1), body len...
-
Article
Open AccessEpigenetically modified AP-2α by DNA methyltransferase facilitates glioma immune evasion by upregulating PD-L1 expression
Programmed death-ligand 1 (PD-L1) ensures that tumor cells escape T-cell-mediated tumor immune surveillance. However, gliomas are characteristic of the low immune response and high-resistance therapy, it is ne...
-
Article
Insight into the pollution characteristics of road and roof runoff in Changsha, China
Non-point source pollution from rainwater runoff presents a serious challenge for urban water management in many cities undergoing urbanization and experiencing climate change. To alleviate water resource conf...
-
Article
Open AccessA clustering linear combination method for multiple phenotype association studies based on GWAS summary statistics
There is strong evidence showing that joint analysis of multiple phenotypes in genome-wide association studies (GWAS) can increase statistical power when detecting the association between genetic variants and ...
-
Article
Open AccessDetoxification enzyme activity, reproductive and developmental fitness of abamectin-resistant Bryobia praetiosa (Acari:Tetranychidae)
Abamectin is an important and environmentally friendly antibiotic pesticide, and its resistance has become an area of intense research. In this study, we employed laboratory bioassays, biochemical analyses, an...
-
Article
Effects of rice-prawn (Macrobrachium nipponense) co-culture on the microbial community of soil
In the Lixiahe region of China, co-culture has been rapidly promoted in flooded paddy fields owing to its ecological and economic benefits. Rice-prawn co-culture can reduce the damage of crab and shrimp to ric...
-
Article
Open AccessMemristor-based analogue computing for brain-inspired sound localization with in situ training
The human nervous system senses the physical world in an analogue but efficient way. As a crucial ability of the human brain, sound localization is a representative analogue computing task and often employed i...
-
Article
Open AccessGene-based association tests using GWAS summary statistics and incorporating eQTL
Although genome-wide association studies (GWAS) have been successfully applied to a variety of complex diseases and identified many genetic variants underlying complex diseases via single marker tests, there i...
-
Article
Open AccessGenome-wide identification of the Capsicum bHLH transcription factor family: discovery of a candidate regulator involved in the regulation of species-specific bioactive metabolites
The basic helix–loop–helix (bHLH) transcription factors (TFs) serve crucial roles in regulating plant growth and development and typically participate in biological processes by interacting with other TFs. Cap...
-
Article
TNFAIP1 Is Upregulated in APP/PS1 Mice and Promotes Apoptosis in SH-SY5Y Cells by Binding to RhoB
Alzheimer’s disease (AD) poses a significant threat to human life and health. The intraneuronal accumulation of β-amyloid (Aβ) plaques in the brains of AD patients results in neuronal cell death, which is a ke...
-
Article
Monitoring of permafrost degradation along the Bei’an-Heihe Expressway in China
We performed a regional geological survey in discontinuous permafrost (PF) area along the Bei’an to Heihe Expressway between September 2009 and October 2016 to investigate the state and change of PF in northea...
-
Article
Open AccessReference intervals of gestational sac, yolk sac, embryonic length, embryonic heart rate at 6–10 weeks after in vitro fertilization-embryo transfer
Accurately determining the normal range of early pregnancy markers can help to predict adverse pregnancy outcomes. The variance in ovulation days leads to uncertain accuracy of reference intervals for natural ...
-
Article
Open AccessSystematic analysis of the Capsicum ERF transcription factor family: identification of regulatory factors involved in the regulation of species-specific metabolites
ERF transcription factors (TFs) belong to the Apetala2/Ethylene responsive Factor (AP2/ERF) TF family and play a vital role in plant growth and development processes. Capsorubin and capsaicinoids have relative...
-
Article
TNFAIP1 Mediates Formaldehyde-Induced Neurotoxicity by Inhibiting the Akt/CREB Pathway in N2a Cells
Formaldehyde (FA) is a common air pollutant. Exposure to exogenous FA can cause damage to the nervous system, such as learning and memory impairment, balance dysfunction, and sleep disorders. Excessive product...
-
Article
Novel Low-Complexity Low-Latency Orthogonal Frequency Division Multiplexing Transmitter
Traditional orthogonal frequency division multiplexing (OFDM) transmitter is implemented by exploiting inverse fast Fourier transform (IFFT), up-sampling, and low pass sha** filter (LPSF) modules, which occu...
-
Article
Open AccessJoint Analysis of Multiple Phenotypes in Association Studies based on Cross-Validation Prediction Error
In genome-wide association studies (GWAS), joint analysis of multiple phenotypes could have increased statistical power over analyzing each phenotype individually to identify genetic variants that are associat...
-
Article
Open AccessBased on the Stackelberg game with decode and forward protocol for physical layer security in the heterogeneous wireless networks
Using wireless relay nodes to cooperate is a very important helpful way to improve the physical layer security performance. In this paper, in the presence of an eavesdrop** node between the source and destin...
-
Article
Open AccessBody mass index and lung cancer risk in never smokers: a meta-analysis
Obesity is found to increase the risk of most cancer types, but reduce lung cancer risk in many studies. However, the association between obesity and lung cancer is still controversial, mainly owing to the con...