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  1. Article

    Open Access

    The impact of the duration of the integrated disease management program on COPD-related outcomes

    The aim of this study is to assess the impact of the duration of the integrated disease management (IDM) program on COPD-related outcomes in real-world setting.

    Ching-Hsiung Lin, Yi-Rong Li, Bing-Yen Wang in European Journal of Medical Research (2023)

  2. Article

    Open Access

    Blood monocyte levels predict the risk of acute exacerbations of chronic obstructive pulmonary disease: a retrospective case–control study

    Monocytes were critical cells in the innate immune system. Monocyte recruitment to the lungs is a crucial process of pathophysiology in chronic obstructive pulmonary disease (COPD). Current evidence on the ass...

    Ching-Hsiung Lin, Yi-Rong Li, Pei Ru Lin, Bing-Yen Wang in Scientific Reports (2022)

  3. Article

    Open Access

    Blood tryptase and thymic stromal lymphopoietin levels predict the risk of exacerbation in severe asthma

    Some patients with severe asthma experience exacerbations despite receiving multiple therapy. The risk of exacerbation and heterogeneous response to treatment may be associated with specific inflammatory molec...

    Hsin-Kuo Ko, Shih-Lung Cheng, Ching-Hsiung Lin, Sheng-Hao Lin in Scientific Reports (2021)

  4. Article

    Open Access

    Tiotropium/Olodaterol treatment reduces cigarette smoke extract-induced cell death in BEAS-2B bronchial epithelial cells

    Cigarette smoking is a critical risk factor for the destruction of lung parenchyma or the development of emphysema, which is characteristic of COPD. Disruption of epithelial layer integrity may contribute to l...

    Cheng-hsiung Chen, Yi-Rong Li, Sheng-Hao Lin in BMC Pharmacology and Toxicology (2020)