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Open AccessEnhanced anti-metastatic bioactivity of an IGF-TRAP re-engineered to improve physicochemical properties
The insulin-like growth factor (IGF) axis has been implicated in the progression of malignant disease and identified as a clinically important therapeutic target. Several IGF-1 receptor (IGF-1R) targeting drug...
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Article
Open AccessThe dog prostate cancer (DPC-1) model: a reliable tool for molecular imaging of prostate tumors and metastases
Clinical applicability of newly discovered reagents for molecular imaging is hampered by the lack of translational models. As the dog prostate cancer (DPC-1) model recapitulates in dogs the natural history of ...