25 Result(s)
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Article
Ruisheng LI
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Open AccessThe combination of Schisandrin C and Luteolin synergistically attenuates hepatitis B virus infection via repressing HBV replication and promoting cGAS-STING pathway activation in macrophages
HBV infection can result in severe liver diseases and is one of the primary causes of liver cell carcinoma-related mortality. Liuwei Wuling tablet (LWWL) is a traditional Chinese medicine formula, with a prote...
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Open AccessAuthor Correction: A systems biology-based investigation into the therapeutic effects of Gansui Banxia Tang on reversing the imbalanced network of hepatocellular carcinoma
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Effects of penconazole enantiomers exposure on hormonal disruption in zebrafish Danio rerio (Hamilton, 1822)
PEN is a widely used triazole fungicide, usually used to control grape white rot. In the process of agricultural use, PEN will be scattered to the soil and water environment, which brings certain environmental...
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Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic hepatotoxicity
Psoraleae Fructus (PF) is a well-known traditional herbal medicine in China, and it is widely used for osteoporosis, vitiligo, and other diseases in clinical settings. However, liver injury caused by PF and it...
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Open AccessMetabolomics coupled with integrated approaches reveal the therapeutic effects of higenamine combined with [6]-gingerol on doxorubicin-induced chronic heart failure in rats
This study was aimed to investigate the therapeutic effects and potential mechanism of higenamine combined with [6]-gingerol (HG/[6]-GR) against doxorubicin (DOX)—induced chronic heart failure (CHF) in rats.
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Bioaccumulation and toxic effects of penconazole in earthworms (Eisenia fetida) following soil exposure
As an agricultural fungicide, penconazole (PEN) is widely used and has adverse effects on various organisms. In order to evaluate the ecological safety risks of PEN, the bioaccumulation and toxic effects of PE...
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Open AccessPower quality enhancement and engineering application with high permeability distributed photovoltaic access to low-voltage distribution networks in Australia
Considering power quality problems such as overvoltage and three-phase unbalance caused by high permeability distributed photovoltaic access in low-voltage distribution networks, this paper proposes a comprehe...
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New incompatible pair of TCM: Epimedii Folium combined with Psoraleae Fructus induces idiosyncratic hepatotoxicity under immunological stress conditions
Epimedii Folium (EF) combined with Psoraleae Fructus (PF) is a common modern preparation, but liver injury caused by Chinese patent medicine preparations containing EF and PF has been frequently reported in re...
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Carbamazepine promotes specific stimuli-induced NLRP3 inflammasome activation and causes idiosyncratic liver injury in mice
The occurrence of idiosyncratic drug-induced liver injury (IDILI) is a leading cause of post-marketing safety warnings and withdrawals of drugs. Carbamazepine (CBZ), widely used as an antiepileptic agent, coul...
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Open AccessMetabolomics combined with network pharmacology exploration reveals the modulatory properties of Astragali Radix extract in the treatment of liver fibrosis
Astragali Radix (AR) is widely-used for improving liver fibrosis, but, the mechanism of action has not been systematically explained. This study aims to investigate the mechanism of AR intervention in liver fibro...
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Research on a hybrid LSSVM intelligent algorithm in short term load forecasting
For enhancing the prediction accuracy of power load forecasting, a support vector machine (SVM) prediction model based on wavelet transform and the mutant fruit fly parameter optimization intelligent algorithm...
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1H NMR-based serum metabolomics analysis of the age-related metabolic effects of perinatal exposure to BPA, BPS, BPF, and BPAF in female mice offspring
The widespread application of bisphenols (BPs) in the industry has made them ubiquitous in the environment, causing potential environmental risks. Its unknown impacts on human being have received more and more...
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Open AccessAngiotensin-converting enzyme 2 inhibits lung injury induced by respiratory syncytial virus
Respiratory syncytial virus (RSV) infection is a major cause of severe lower respiratory illness in infants and young children, but the underlying mechanisms responsible for viral pathogenesis have not been fu...
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Open AccessSocio-economic position as an intervention against overweight and obesity in children: a systematic review and meta-analysis
Studies that investigated the association between socio-economic position (SEP) and obesity in children suggest inconsistent results. The aim of this study is to summarize and quantify the current evidence on ...
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Open AccessLarge dose means significant effect – dose and effect relationship of Chi-Dan-Tui-Huang decoction on alpha-naphthylisothiocyanate-induced cholestatic hepatitis in rats
Large dose application of traditional Chinese medicines has attracted more and more attentions in recent years. However, the scientific connotation of large dose application has not been clarified so far. The ...
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Study on hot property differences of Aconiti Lateralis Radix Praeparata and its compatibility with different ginger processed products based on bio-thermodynamics
Aconiti Lateralis Radix Praeparata (ALRP) is commonly used traditional Chinese medicine in clinic, and it is usually in compatibility with ginger including Zingiberis Rhizoma (ZR), Zingiberis Rhi...
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Microcalorimetric investigation of five Aconitum L. plants on the metabolic activity of mitochondria isolated from rat liver
The fact that mitochondria still have metabolic activity and can live for a week with appropriate nutrients after isolated from the rat liver provides us a useful means to investigate the metabolic process of ...
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Open AccessIncreased level of nucleolin confers to aggressive tumor progression and poor prognosis in patients with hepatocellular carcinoma after hepatectomy
Nucleolin, as a multifunctional protein, has been demonstrated to play an oncogenic role in human hepatocellular carcinoma (HCC). The aim of this study was to investigate the expression pattern of nucleolin in...
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p-Synephrine suppresses lipopolysaccharide-induced acute lung injury by inhibition of the NF-κB signaling pathway
We investigated whether p-synephrine exerts potent anti-inflammatory effects against acute lung injury (ALI) induced by lipopolysaccharide (LPS) in vivo, and we further investigated the inhibitory mechanism of p-...
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Open AccessA systems biology-based investigation into the therapeutic effects of Gansui Banxia Tang on reversing the imbalanced network of hepatocellular carcinoma
Several complex molecular events are involved in tumorigenesis of hepatocellular carcinoma (HCC). The interactions of these molecules may constitute the HCC imbalanced network. Gansui Banxia Tang (GSBXT), as a...
