10 Result(s)
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Article
Rui Mao
Life Sciences
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Article
DAE-Mask: a novel deep-learning-based automatic detection model for in-field wheat diseases
Wheat diseases seriously restrict the safety of wheat production and food quality. For farmers and agriculture technicians, diagnosing the disease with the naked eye is not suitable for modern precision agricu...
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Association of Plasma Metal Levels with Outcomes of Assisted Reproduction in Polycystic Ovary Syndrome
The objective of this study is to explore the correlation of metal levels with assisted reproductive technology (ART) outcomes in polycystic ovary syndrome (PCOS) patients. The individuals were recruited who m...
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Open AccessImpairments of GABAergic transmission in hippocampus mediate increased susceptibility of epilepsy in the early stage of Alzheimer’s disease
Patients with Alzheimer’s disease (AD) are often co-morbid with unprovoked seizures, making clinical diagnosis and management difficult. Although it has an important role in both AD and epilepsy, abnormal γ-am...
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Open Accessc-Jun as a one-way valve at the naive to primed interface
c-Jun is a proto-oncogene functioning as a transcription factor to activate gene expression under many physiological and pathological conditions, particularly in somatic cells. However, its role in early embry...
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Open AccessJCBIE: a joint continual learning neural network for biomedical information extraction
Extracting knowledge from heterogeneous data sources is fundamental for the construction of structured biomedical knowledge graphs (BKGs), where entities and relations are represented as nodes and edges in the...
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Open AccessDNAJB8 in small extracellular vesicles promotes Oxaliplatin resistance through TP53/MDR1 pathway in colon cancer
Chemotherapy is one of the most frequently used therapies for the treatment of colon cancer (COAD). However, Oxaliplatin (L-OHP) resistance is a major obstacle to the effective treatment of COAD. Here, we inve...
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Open AccessCircNPHP4 in monocyte-derived small extracellular vesicles controls heterogeneous adhesion in coronary heart atherosclerotic disease
Small extracellular vesicles (sEVs)-derived circular RNAs (circRNAs) could regulate gene expression in recipient cells, and dysregulation of sEVs-derived circRNAs has been implicated in several diseases. Howev...
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Fire lines as fault lines: increased trade barriers during the COVID-19 pandemic further shatter the global food system
In this opinion piece, we highlight that trade barriers established during COVID-19 as “fire lines” to prevent cross-border transmission of the pandemic could become “fault lines” that demolish the global food...
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Open AccessThe lncRNA RP11-142A22.4 promotes adipogenesis by sponging miR-587 to modulate Wnt5β expression
Emerging evidence suggests that long noncoding RNAs (lncRNAs) play essential roles in the regulation of gene expression. However, the functional contributions of lncRNAs to adipogenesis remain largely unexplor...
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The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells
The transcriptional regulation of haematopoietic stem cell quiescence is only starting to be understood. The nuclear transcription factor Nurr1 drives early haematopoietic progenitors into quiescence through t...
