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  1. Article

    Open Access

    CDK5RAP2 is a Wnt target gene and promotes stemness and progression of oral squamous cell carcinoma

    In oral squamous cell carcinoma (OSCC), a highly aggressive and frequently lethal malignancy, the role and action mechanism of the microtubule regulatory protein CDK5RAP2 have not been fully understood. Here, ...

    Yuehong Shen, Yuling Chen, Yuntao Lin, Yicun Li, Pengfei Liu… in Cell Death & Disease (2023)

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  2. No Access

    Article

    Epigenetic Alterations of Wnt Signaling Pathways in Nasopharyngeal Carcinoma

    The purpose of this study is to discuss the epigenetic alterations of Wnt signaling pathways in nasopharyngeal carcinoma.

    Pengfei Liu, Lu Fu, Robert Z. Qi in Current Pharmacology Reports (2018)

  3. Article

    Open Access

    The catalytic subunit of DNA polymerase δ inhibits γTuRC activity and regulates Golgi-derived microtubules

    γ-Tubulin ring complexes (γTuRCs) initiate microtubule growth and mediate microtubule attachment at microtubule-organizing centers, such as centrosomes and the Golgi complex. However, the mechanisms that contr...

    Yuehong Shen, Pengfei Liu, Taolue Jiang, Yu Hu, Franco K. C. Au… in Nature Communications (2017)

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  4. No Access

    Article

    The neuronal p35 activator of Cdk5 is a novel F-actin binding and bundling protein

    The neuronal Cdk5 activator p35 is involved in a multitude of neuronal activities, including cytoskeletal organization. We show here that p35 directly interacts with filamentous actin (F-actin) but not with mo...

    Lisheng He, Zhaojun Zhang, Yan Yu, Sohail Ahmed… in Cellular and Molecular Life Sciences (2011)