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Article
High sensitivity to carcinogens in the brain of a mouse model of Alzheimer's disease
Cancer and Alzheimer's disease (AD) are commonly found among elderly patients. Chronic inflammation is the characteristic of both diseases. Amyloid-β peptide is the main inducer of inflammation in AD. Moreover...
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Article
Chemical heterogeneity in adult rat cerebellar purkinje cells as revealed by zebrin I and low-affinity nerve growth factor receptor immunocytochemical expression following injury
Cerebellar Purkinje cells in rat express low-affinity nerve growth factor receptor during development, but rarely in normal adult animals. However, after either mechanical injury or colchicine treatment during...
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Article
Distribution of enkephalin-immunoreactive nerve fibres and terminals in the region of the nucleus basalis magnocellularis of the rat: a light and electron microscopic study
This investigation was carried out on the distribution of enkephalin-containing nerve fibres and terminals in the region of the nucleus basalis magnocellularis (NBM) of the rat. At the light microscope (LM) le...
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Article
Separation of specific fractions of synaptosomes by affinity chromatography
The authors describe a new technique for isolation of specific fractions of synaptosomes, on the basis of their surface glycoproteins, by affinity chromatography using lectin-Sepharose columns.