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Article
Spontaneous X chromosome MI and MII nondisjunction events in Drosophila melanogaster oocytes have different recombinational histories
Recent studies of human oocytes have demonstrated an enrichment for distal exchanges among meiosis I (MI) nondisjunction events and for proximal exchanges among meiosis II (MII) events. Our characterization of...
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Article
Playing for half the deck: the molecular biology of meiosis
Meiosis reduces the number of chromosomes carried by a diploid organism by half, partitioning precisely one haploid genome into each gamete. The basic events of meiosis reflect three meiosis-specific processes...
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Article
Homologous chromosome interactions in meiosis: diversity amidst conservation
One of the unique aspects of meiosis is the pairing and exchange of information between homologous chromosomes.
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Article
RNF212 marks the spot
A new study in mice shows that, during meiosis, the decision to mature a double-strand break into a crossover is controlled by a dosage-sensitive regulator, RNF212. This finding provides insight into the cross...
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Article
Tetrad analysis in the mouse
Meiotic tetrad analysis is a powerful tool for analyzing all four products of a single meiosis. A new method for tetrad analysis in mammals provides valuable insights into the mechanisms that mediate the excha...