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Article
Open AccessDiabetic uterus environment may play a key role in alterations of DNA methylation of several imprinted genes at mid-gestation in mice
Maternal diabetes mellitus not only has severe deleterious effects on fetal development, but also it affects transmission to the next generation. However, the underlying mechanisms for these effects are still ...
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Article
Open AccessMaternal obesity and diabetes may cause DNA methylation alteration in the spermatozoa of offspring in mice
The adverse effects on offspring of diabetic and/or obese mothers can be passed to the next generation. However, the mechanisms behind this are still unclear. Epigenetics may play a key role during this process.
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Article
Open AccessPolymorphisms in estrogen receptors predict the risk of male infertility: a meta-analysis
Estrogen receptors play an important role in mediating estrogen action on target tissues, and the estrogen is relevant to male infertility. Single nucleotide polymorphisms (SNPs) in estrogen receptors may be a...