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  1. Article

    Open Access

    Diabetic uterus environment may play a key role in alterations of DNA methylation of several imprinted genes at mid-gestation in mice

    Maternal diabetes mellitus not only has severe deleterious effects on fetal development, but also it affects transmission to the next generation. However, the underlying mechanisms for these effects are still ...

    Zhao-Jia Ge, Qiu-**a Liang, Shi-Ming Luo in Reproductive Biology and Endocrinology (2013)

  2. Article

    Open Access

    Maternal obesity and diabetes may cause DNA methylation alteration in the spermatozoa of offspring in mice

    The adverse effects on offspring of diabetic and/or obese mothers can be passed to the next generation. However, the mechanisms behind this are still unclear. Epigenetics may play a key role during this process.

    Zhao-Jia Ge, Qiu-**a Liang, Yi Hou, Zhi-Ming Han in Reproductive Biology and Endocrinology (2014)

  3. Article

    Open Access

    Polymorphisms in estrogen receptors predict the risk of male infertility: a meta-analysis

    Estrogen receptors play an important role in mediating estrogen action on target tissues, and the estrogen is relevant to male infertility. Single nucleotide polymorphisms (SNPs) in estrogen receptors may be a...

    Tian-Fu Li, Qiu-Yue Wu, Cui Zhang, Wei-Wei Li in Reproductive Biology and Endocrinology (2014)