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Article
ROCK: a breast cancer functional genomics resource
The clinical and pathological heterogeneity of breast cancer has instigated efforts to stratify breast cancer sub-types according to molecular profiles. These profiling efforts are now being augmented by large...
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Article
ROCK: a resource for integrative breast cancer data analysis
Given the steady increase in breast cancer rates in both the developed and develo** world, there has been a concerted research effort undertaken worldwide to understand the molecular mechanisms underpinning ...
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Article
Open AccessTumour kinome re-wiring governs resistance to palbociclib in oestrogen receptor positive breast cancers, highlighting new therapeutic modalities
Combination of CDK4/6 inhibitors and endocrine therapy improves clinical outcome in advanced oestrogen receptor (ER)-positive breast cancer, however relapse is inevitable. Here, we show in model systems that o...