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  1. Article

    Open Access

    AMPK targets PDZD8 to trigger carbon source shift from glucose to glutamine

    The shift of carbon utilization from primarily glucose to other nutrients is a fundamental metabolic adaptation to cope with decreased blood glucose levels and the consequent decline in glucose oxidation. AMP-...

    Mengqi Li, Yu Wang, **aoyan Wei, Wei-Feng Cai, Jianfeng Wu, Mingxia Zhu in Cell Research (2024)

  2. Article

    Open Access

    Functional investigation of SLC1A2 variants associated with epilepsy

    Epilepsy is a common neurological disorder and glutamate excitotoxicity plays a key role in epileptic pathogenesis. Astrocytic glutamate transporter GLT-1 is responsible for preventing excitotoxicity via clear...

    Qi Qu, Wenlong Zhang, Ji Wang, Dongmei Mai, Siqiang Ren in Cell Death & Disease (2022)