3,572 Result(s)

Article

Bisphenol S causes excessive estrogen synthesis by activating FSHR and the downstream cAMP/PKA signaling pathway

Estrogen excess in females has been linked to a diverse array of chronic and acute diseases. Emerging research shows that exposure to estrogen-like compounds such as bisphenol S leads to increases in 17β-estradio...

**aorong Zhang, **nda Zhang, Zhenzhong Zhang, Yijiao Shi… in Communications Biology (2024)

Article

Publisher Correction: Restrained Mitf-associated autophagy by Mulberroside A ameliorates osteoclastogenesis and counteracts OVX-Induced osteoporosis in mice

Hong Xue, Zhenhua Feng, Putao Yuan, Li Qiao, Qiliang Lou… in Cell Death Discovery (2024)

Article

Correction: Recruitment of LEF1 by Pontin chromatin modifier amplifies TGFBR2 transcription and activates TGFβ/SMAD signalling during gliomagenesis

Xuexia Zhou, Xuebing Li, Run Wang, Dan Hua, Cuiyun Sun, Lin Yu… in Cell Death & Disease (2024)

Article

Inhibition of PKC-δ retards kidney fibrosis via inhibiting cGAS-STING signaling pathway in mice

Kidney fibrosis is considered to be the ultimate aggregation pathway of chronic kidney disease (CKD), but its underlying mechanism remains elusive. Protein kinase C-delta (PKC-δ) plays critical roles in the co...

Dongyun Wang, Yue Li, Guiying Li, Mengyu Liu, Zihui Zhou, Ming Wu… in Cell Death Discovery (2024)

Article

Tracking the hologenome dynamics in aquatic invertebrates by the holo-2bRAD approach

The “hologenome” concept is an increasingly popular way of thinking about microbiome-host for marine organisms. However, it is challenging to track hologenome dynamics because of the large amount of material, ...

Cen Ma, Chang Xu, Tianqi Zhang, Qianqian Mu, Jia Lv, Qiang **ng… in Communications Biology (2024)

Article

Phase separation of RNF214 promotes the progression of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors, and the expression and function of an uncharacterized protein RNF214 in HCC are still unknown. Phase separation has recently been obse...

Zheng-Jie He, Ke He, Song-Wang Cai, Rui Zhang, Zhong-Bao Shao… in Cell Death & Disease (2024)

Article

Metaproteomics-informed stoichiometric modeling reveals the responses of wetland microbial communities to oxygen and sulfate exposure

Climate changes significantly impact greenhouse gas emissions from wetland soil. Specifically, wetland soil may be exposed to oxygen (O₂) during droughts, or to sulfate (SO₄^2-) as a result of sea level rise. How ...

Dongyu Wang, Pieter Candry, Kristopher A. Hunt… in npj Biofilms and Microbiomes (2024)

Article

Author Correction: High-yield porphyrin production through metabolic engineering and biocatalysis

Haihong Chen, Yaohong Wang, Weishan Wang, Ting Cao, Lu Zhang… in Nature Biotechnology (2024)

Article

CRISPR-based genome editing of a diurnal rodent, Nile grass rat (Arvicanthis niloticus)

Diurnal and nocturnal mammals have evolved distinct pathways to optimize survival for their chronotype-specific lifestyles. Conventional rodent models, being nocturnal, may not sufficiently recapitulate the bi...

Huirong **e, Katrina Linning-Duffy, Elena Y. Demireva, Huishi Toh… in BMC Biology (2024)

Article

Pig blastocyst-like structure models from embryonic stem cells

Pluripotent stem cells have the potential to generate embryo models that can recapitulate developmental processes in vitro. Large animals such as pigs may also benefit from stem-cell-based embryo models for im...

**zhu **ang, Hanning Wang, Bingbo Shi, Jiajun Li, Dong Liu, Kaipeng Wang… in Cell Discovery (2024)

Article

Genome-wide association study provided insights into the polled phenotype and polled intersex syndrome (PIS) in goats

Breeding polled goats is a welfare-friendly approach for horn removal in comparison to invasive methods. To gain a comprehensive understanding of the genetic basis underlying polledness in goats, we conducted ...

Fuhong Zhang, Qingqing Liu, ** Gong, Yaling Wang, Chenbo Shi, Lu Zhu… in BMC Genomics (2024)

Article

Influenza virus uses mGluR2 as an endocytic receptor to enter cells

Influenza virus infection is initiated by the attachment of the viral haemagglutinin (HA) protein to sialic acid receptors on the host cell surface. Most virus particles enter cells through clathrin-mediated e...

Zixin Ni, **liang Wang, **aofei Yu, Yifan Wang, **gfei Wang… in Nature Microbiology (2024)

Article

S100A8/A9^hi neutrophils induce mitochondrial dysfunction and PANoptosis in endothelial cells via mitochondrial complex I deficiency during sepsis

S100a8/a9, largely released by polymorphonuclear neutrophils (PMNs), belongs to the S100 family of calcium-binding proteins and plays a role in a variety of inflammatory diseases. Although S100a8/a9 has been r...

Yanghanzhao Wang, Yuxin Shi, Yuwen Shao, **hua Lu, Hao Zhang… in Cell Death & Disease (2024)

Article

Regulation of endocrine cell alternative splicing revealed by single-cell RNA sequencing in type 2 diabetes pathogenesis

The prevalent RNA alternative splicing (AS) contributes to molecular diversity, which has been demonstrated in cellular function regulation and disease pathogenesis. However, the contribution of AS in pancreat...

** Wang, Shiyi Wen, Minqi Chen, Jiayi **e, **nhua Lou… in Communications Biology (2024)

Article

TNIP3 protects against pathological cardiac hypertrophy by stabilizing STAT1

Pathological cardiac hypertrophy is one of the major risk factors of heart failure and other cardiovascular diseases. However, the mechanisms underlying pathological cardiac hypertrophy remain largely unknown....

Hongjie Shi, Yongjie Yu, Dajun Li, Kun Zhu, Xu Cheng, Tengfei Ma… in Cell Death & Disease (2024)