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Open AccessCircular olefin copolymers made de novo from ethylene and α-olefins
Ethylene/α-olefin copolymers are produced in huge scale and widely used, but their after-use disposal has caused plastic pollution problems. Their chemical inertness made chemical re/upcycling difficult. Ideal...
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Article
Fabrication and Performance of Gemini Oleamidopropyl Hydroxy Sulfobetaine (GOHSB) Used as a Viscoelastic Fracturing Fluid
Gemini oleamidopropyl hydroxy sulfobetaine (GOHSB) was prepared and characterized. The CMC of GOHSB was 7.19 × 10–5 and 8.74 × 10–5 mol/L, and the surface tension of GOHSB and gel breaking liquid was 31.7 and 48....
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Article
Envision A Bright Future to Heal Your Negative Mood: A Trial in China
Mental imagery can help people have meaningful experiences and improve their mental and physical health. This study aimed to explore the intervention effect of positive mental imagery training (imagery cogniti...
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Article
A support vector machine based semiparametric mixture cure model
The mixture cure model is an extension of standard survival models to analyze survival data with a cured fraction. Many developments in recent years focus on the latency part of the model to allow more flexibl...
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Article
Preparation and properties of a novel waterborne fluorinated polyurethane–acrylate hybrid emulsion modified by long aliphatic chains
Waterborne fluorinated polyurethane–acrylate hybrid emulsion modified by long aliphatic chains (WFPUA) is prepared by two steps, which include that the stearyl alcohol (SA)-blocked (end-capped) polyurethanes (...
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Article
Open AccessPredictive and preventive significance of AMPK activation on hepatocarcinogenesis in patients with liver cirrhosis
Metformin has been demonstrated to prevent hepatocellular carcinoma (HCC). Metformin acts mainly by phosphorylation of AMPK. However, the phosphorylation status of AMPK and its role in the prediction and preve...
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Article
NLRP3 Deletion Inhibits the Non-alcoholic Steatohepatitis Development and Inflammation in Kupffer Cells Induced by Palmitic Acid
The cleavage and secretion of pro-inflammatory cytokines IL-1β and IL-18 is regulated by NLRP3 (NACHT, LRR, and PYD domain-containing protein 3) inflammasome activation. Kupffer cells (KCs) are implicated in t...
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Article
PI3K inhibition protects mice from NAFLD by down-regulating CMKLR1 and NLRP3 in Kupffer cells
Inflammation induced by high-fat diet (HFD) is of critical importance in the development of hepatic steatosis. The role of chemerin in the progress of nonalcoholic fatty liver disease (NAFLD) remains controver...
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Article
Self-assembly properties of hydrophobically associating perfluorinated polyacrylamide in dilute and semi-dilute solutions
Hydrophobically associating perfluorinated polyacrylamide (HACFP) is a kind of novel cationic polyacrylamide prepared with acrylamide (AM), methacryloxyethyl trimethylammonium chloride (DMC) and 2-(perfluorohe...
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Article
Study on properties of waterborne fluorinated polyurethane/acrylate hybrid emulsion and films
Waterborne fluorinated polyurethane acrylate (WFPUA) with the different content of HEA were successfully obtained by introducing the fluorinated monomers both in polyurethane and polyacrylate. In our study, th...
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Article
S-Adenosylmethionine attenuates lipopolysaccharide-induced liver injury by downregulating the Toll-like receptor 4 signal in Kupffer cells
S-Adenosylmethionine (SAM) is beneficial for lipopolysaccharide (LPS)-induced liver injury, but its molecular basis is not fully understood. The present study was carried out to investigate the...
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Article
Preparation and properties of a novel waterborne fluorinated polyurethane–acrylate hybrid emulsion
The waterborne fluorinated polyurethane–acrylate hybrid emulsion (WFPUA) was prepared by two steps, including the preparation of the fluorinated alcohol blocked polyurethanes (FBPU) in the mixtures of vinyl mo...
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Article
The Effects of Twist-2 on Liver Endotoxin Tolerance Induced by a Low Dose of Lipopolysaccharide
Endotoxin tolerance is an important mechanism for preventing uncontrolled inflammatory cytokine production in bacterial sepsis. However, its molecular mechanisms remain largely unknown. It was reported that Tw...
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Article
Preparation and self-assembly properties of silicone-modified hydrophobically associating polyacrylamide
Silicone-modified hydrophobically associating polyacrylamide (USPAM) was prepared by emulsifier-free ultrasonically assisted radical polymerization with acrylamide (AM), dimethylvinylphenylsilane (DMPS), and 2...
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Article
Effect of cosolvent NMP on properties of cationic fluorocarbon emulsifier-free emulsion
Cationic fluorocarbon emulsifier-free emulsion was prepared via a novel method of adding organic cosolvent N-methylpyrrolidone (NMP), which was characteristic of the reaction transferring from solution to emulsio...
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Article
Radiofrequency-Assisted Versus Clamp-Crushing Parenchyma Transection in Cirrhotic Patients with Hepatocellular Carcinoma: A Randomized Clinical Trial
Surgical resection remains the optimal therapy for cirrhotic patients with hepatocellular carcinoma (HCC) that are not suitable for liver transplantation (LT). Recently, various innovative techniques for liver...
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Article
Effect of cationic monomer on properties of cationic fluorocarbon emulsifier-free emulsion
Cationic fluorocarbon emulsifier-free emulsion (CFE) was prepared by a novel method, which was characteristic of the phase-inversion polymerization from solution to emulsion. The stability mechanism of the CFE...
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Article
Study on preparation and self-assembly properties of hydrophobically associating polyacrylamide by emulsifier-free ultrasonic assisted radical polymerization
Through ultrasonic assisted radical polymerization, hydrophobically associating polyacrylamide (U-HAPAM) was prepared by acrylamide (AM), 2-acrylamido −2- methyl propane sulfonic acid (AMPS), and hydrophobic m...
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Article
Study on the self-assembly properties of fluorinated hydrophobically associating polyacrylamide
The self-assembly of a fluorinated hydrophobically associating polyacrylamide (UFPAM) prepared by emulsifier-free ultrasound-assisted radical polymerization was studied using fluorescence spectroscopy (FS), rh...
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Article
Study on preparation and solution properties of hydrophobically associating polyacrylamide by emulsifier-free ultrasonic assisted radical polymerization
Through ultrasonic assisted radical polymerization, hydrophobically associating polyacrylamide (U-HAPAM) was prepared by acrylamide (AM), 2-acrylamido -2- methyl propane sulfonic acid (AMPS), and long-aliphati...