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    Single-cell transcriptome analysis identifies novel biomarkers involved in major liver cancer subtypes

    Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are the two aggressive subtypes of liver cancer (LC). Immense cellular heterogeneity and cross-talk between cancer and healthy cells mak...

    Asish Kumar Swain, Prashant Pandey, Riddhi Sera in Functional & Integrative Genomics (2023)

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    The seesaw of diet restriction and lifespan: lessons from Drosophila studies

    Diet restriction (DR) studies undergo the implementation of reduced single or multiple component/s of the fly food without causing malnutrition. The question of how and why DR modifies the fate of lifespan in ...

    Sudhakar Krittika, Pankaj Yadav in Biogerontology (2021)

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    An overview of two decades of diet restriction studies using Drosophila

    Dietary restriction (DR) is a potent forerunner in aging studies capable of influencing lifespan and improving health in various model organisms even in their old age. Despite the importance of protein and car...

    Sudhakar Krittika, Pankaj Yadav in Biogerontology (2019)

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    Circadian clocks of faster develo** fruit fly populations also age faster

    Age-related changes in circadian rhythms have been studied in several model organisms including fruit flies Drosophila melanogaster. Although a general trend of period (τ) lengthening, reduction in rhythm strengt...

    Pankaj Yadav, Vijay Kumar Sharma in Biogerontology (2014)