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Article
Single-cell transcriptome analysis identifies novel biomarkers involved in major liver cancer subtypes
Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) are the two aggressive subtypes of liver cancer (LC). Immense cellular heterogeneity and cross-talk between cancer and healthy cells mak...
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Article
The seesaw of diet restriction and lifespan: lessons from Drosophila studies
Diet restriction (DR) studies undergo the implementation of reduced single or multiple component/s of the fly food without causing malnutrition. The question of how and why DR modifies the fate of lifespan in ...
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Article
An overview of two decades of diet restriction studies using Drosophila
Dietary restriction (DR) is a potent forerunner in aging studies capable of influencing lifespan and improving health in various model organisms even in their old age. Despite the importance of protein and car...
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Article
Circadian clocks of faster develo** fruit fly populations also age faster
Age-related changes in circadian rhythms have been studied in several model organisms including fruit flies Drosophila melanogaster. Although a general trend of period (τ) lengthening, reduction in rhythm strengt...