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Genome editing for food, nutrition, and health
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Identification of hub genes to determine drug-disease correlation in breast carcinomas
The exact molecular mechanism underlying the heterogeneous drug response against breast carcinoma remains to be fully understood. It is urgently required to identify key genes that are intricately associated w...
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Article
Open Science: Challenges, Possible Solutions and the Way Forward
Everyone agrees that scientific communication should be free for all. Unfortunately, accessing publications from many reputed journals comes at a high cost—a cost that many researchers and institutions cannot ...
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Non-coding RNAs: the silent regulators of health and diseases
Non-coding RNAs (ncRNAs) like miRNAs, siRNA, lncRNAs, circRNAs, piRNAs, snoRNAs, snRNAs etc. form a collective group of RNAs that is instrumental to the various functions of the genome. With the advent of cutt...
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Article
Exploring the crosstalk between long non-coding RNAs and microRNAs to unravel potential prognostic and therapeutic biomarkers in β-thalassemia
β-thalassemia is a prevalent monogenic disorder characterized by reduced or absent synthesis of the β-globin chain. Although great effort has been made to ameliorate the disease severity of β-thalassemic patie...
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Revisiting fetal hemoglobin inducers in beta-hemoglobinopathies: a review of natural products, conventional and combinatorial therapies
Beta-hemoglobinopathies exhibit a heterogeneous clinical picture with varying degrees of clinical severity. Pertaining to the limited treatment options available, where blood transfusion still remains the comm...
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Article
Genetic Disorders, Genoty** Techniques and the Emerging Role of Tetra-ARMS-PCR as a Diagnostic Tool
Minor deviations in the script of human life (the genetic code) are known to have major consequences on human health and well-being. Even substitution of a single nucleotide (single nucleotide polymorphism — S...