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  1. Article

    Open Access

    Defining consensus leukemia-associated immunophenotypes for detection of minimal residual disease in acute myeloid leukemia in a multicenter setting

    Flow-cytometric detection of minimal residual disease (MRD) has proven in several single-institute studies to have an independent prognostic impact. We studied whether this relatively complex approach could be...

    N Feller, V H J van der Velden, R A Brooimans, N Boeckx, F Preijers… in Blood Cancer Journal (2013)

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  2. No Access

    Article

    Functional detection of MDR1/P170 and MRP/P190-mediated multidrug resistance in tumour cells by flow cytometry

    Multidrug resistance (MDR) in tumour cells is often caused by the overexpression of the plasma membrane drug transporter P-glycoprotein (P-gp) or the recently discovered multidrug resistance-associated protein...

    N Feller, CM Kuiper, J Lankelma, JK Ruhdal, RJ Scheper… in British Journal of Cancer (1995)

  3. No Access

    Article

    Cortisol is transported by the multidrug resistance gene product P-glycoprotein

    The physiology of the multidrug transporter P-glycoprotein (Pgp) is still poorly understood. We now show evidence that cell lines with a high expression of Pgp display a reduced accumulation of cortisol and an...

    CK van Kalken, HJ Broxterman, HM Pinedo, N Feller, H Dekker… in British Journal of Cancer (1993)