4 Result(s)
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Cancer Research
Drug Resistance
Molecular Medicine
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Article
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Article
Open AccessBladder cancer: worse survival in women from deprived areas
In a case-note review of 120 women and 227 men presenting with muscle-invasive bladder tumours in 1998, survival was worse for women in 3 years of follow-up, with the greatest difference, of 19.9%, at 6 months...
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Article
Open AccessFunctional epigenomics approach to identify methylated candidate tumour suppressor genes in renal cell carcinoma
Promoter region hypermethylation and transcriptional silencing is a frequent cause of tumour suppressor gene (TSG) inactivation in many human cancers. Previously, to identify candidate epigenetically inactivat...
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Open AccessInfluence of omega-6 PUFA arachidonic acid and bone marrow adipocytes on metastatic spread from prostate cancer
Prostate cancer (CaP) preferentially metastasises to the bone, and we have previously shown that the poly-unsaturated fatty acid (PUFA) arachidonic acid (AA) is a potent stimulator of CaP invasion. Here we pre...
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Article
Open AccessThe differential effects of statins on the metastatic behaviour of prostate cancer
Although statins do not affect the incidence of prostate cancer (CaP), usage reduces the risk of clinical progression and mortality. Although statins are known to downregulate the mevalonate pathway, the mecha...
