4 Result(s)

Article

Loss of LECT2 promotes ovarian cancer progression by inducing cancer invasiveness and facilitating an immunosuppressive environment

Leukocyte cell-derived chemotaxin 2 (LECT2) is a multifunctional cytokine that can bind to several receptors and mediate distinct molecular pathways in various cell settings. Changing levels of LECT2 have been...

Chin-Jui Wu, Ke-Fan Pan, Ji-Qing Chen, Yu -Chen Tao, Yu-Cheng Liu, Bo-Rong Chen… in Oncogene (2024)

Article

Correction: Non-enzymatic heparanase enhances gastric tumor proliferation via TFEB-dependent autophagy

Min Yang, Bo Tang, Sumin Wang, Li Tang, Dalin Wen, Israel Vlodavsky… in Oncogenesis (2023)

Article

Non-enzymatic heparanase enhances gastric tumor proliferation via TFEB-dependent autophagy

Heparanase (HPA) is the predominant enzyme that cleaves heparan sulfate and plays a critical role in a variety of pathophysiological processes. HPA activity has been traditionally correlated with tumor metasta...

Min Yang, Bo Tang, Sumin Wang, Li Tang, Dalin Wen, Israel Vlodavsky… in Oncogenesis (2022)

Article

Wild-type p53 upregulates an early onset breast cancer-associated gene GAS7 to suppress metastasis via GAS7–CYFIP1-mediated signaling pathway

The early onset breast cancer patients (age ≤ 40) often display higher incidence of axillary lymph node metastasis, and poorer five-year survival than the late-onset patients. To identify the genes and molecul...

Jer-Wei Chang, Wen-Hung Kuo, Chiao-Mei Lin, Wen-Ling Chen, Shih-Hsuan Chan… in Oncogene (2018)