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The proteasome regulator PSME4 modulates proteasome activity and antigen diversity to abrogate antitumor immunity in NSCLC

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  1. Article

    Open Access

    The survival and function of IL-10-producing regulatory B cells are negatively controlled by SLAMF5

    B cells have essential functions in multiple sclerosis and in its mouse model, experimental autoimmune encephalomyelitis, both as drivers and suppressors of the disease. The suppressive effects are driven by a...

    Lihi Radomir, Matthias P. Kramer, Michal Perpinial in Nature Communications (2021)

  2. Article

    Open Access

    Golgi organization is regulated by proteasomal degradation

    The Golgi is a dynamic organelle whose correct assembly is crucial for cellular homeostasis. Perturbations in Golgi structure are associated with numerous disorders from neurodegeneration to cancer. However, w...

    Avital Eisenberg-Lerner, Ron Benyair, Noa Hizkiahou, Neta Nudel in Nature Communications (2020)