3 Result(s)
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Article
Matthew D Hall
Life Sciences
Biochemistry, general
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Article
Surrounded by ligands: the reactivity of cisplatin in cell culture medium
The reactivity of platinum-containing drugs such as cisplatin, carboplatin, and oxaliplatin is essential for its mechanism of action as an anticancer agent. This inherent reactivity means that molecules in too...
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Article
Evaluation of fluorophore-tethered platinum complexes to monitor the fate of cisplatin analogs
The platinum drugs cisplatin, carboplatin, and oxaliplatin are highly utilized in the clinic and as a consequence have been extensively studied in the laboratory setting, sometimes by generating fluorophore-ta...
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Article
The cellular distribution and oxidation state of platinum(II) and platinum(IV) antitumour complexes in cancer cells
The cellular distribution of platinum in A2780 ovarian cancer cells treated with cisplatin and platinum(IV) complexes with a range of reduction potentials has been examined using elemental analysis (synchrotro...
