82 Result(s)
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Article
Masahiro Sugiura
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Article
Open AccessPhotoisomerization pathway of the microbial rhodopsin chromophore in solution
Photoisomerization is a key photochemical reaction in microbial and animal rhodopsins. It is well established that such photoisomerization is highly selective; all-trans to 13-cis, and 11-cis to all-trans forms i...
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PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma
PBRM1 encodes an accessory subunit of the PBAF SWI/SNF chromatin remodeller, and the inactivation of PBRM1 is a frequent event in kidney cancer. However, the impact of PBRM1 loss on chromatin remodelling is not w...
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Rhodopsin-bestrophin fusion proteins from unicellular algae form gigantic pentameric ion channels
Many organisms sense light using rhodopsins, photoreceptive proteins containing a retinal chromophore. Here we report the discovery, structure and biophysical characterization of bestrhodopsins, a microbial rh...
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Open AccessThe heavy chain of 4F2 antigen promote prostate cancer progression via SKP-2
The 4F2 cell-surface antigen heavy chain (4F2hc) forms a heterodimeric complex with L-type amino acid transporter 1 (LAT1) and transports large neutral essential amino acids. However, in contrast to the tradit...
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Open AccessStructural insights into the mechanism of rhodopsin phosphodiesterase
Rhodopsin phosphodiesterase (Rh-PDE) is an enzyme rhodopsin belonging to a recently discovered class of microbial rhodopsins with light-dependent enzymatic activity. Rh-PDE consists of the N-terminal rhodopsin...
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Open AccessExpression of L-type amino acid transporter 1 as a molecular target for prognostic and therapeutic indicators in bladder carcinoma
L-type amino acid transporter 1 (LAT1) plays a role in transporting essential amino acids including leucine, which regulates the mTOR signaling pathway. Here, we studied the expression profile and functional r...
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Processing of the 5′-UTR and existence of protein factors that regulate translation of tobacco chloroplast psbN mRNA
The chloroplast psbB operon includes five genes encoding photosystem II and cytochrome b 6 /f complex components. The psbN gene is located on the opposite strand. PsbN is localized...
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Enantioselective Hydrogenation of Olefins using Commercially Available Pd/C. Chiral Heterogeneous Catalyst Applicable for High-Throughput Screening
Cinchonidine-modified Pd/C applicable for the high-throughput-guided study was developed. Commercial Pd/C catalysts were employed for the enantioselective hydrogenation of phenylcinnamic acid after the pretrea...
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XAFS and XRD Analysis of Ceria–Zirconia Oxygen Storage Promoters for Automotive Catalysts
Three types of CeO2–ZrO2 (Ce:Zr = 1:1 molar ratio) compounds with different oxygen storage/release capacity (OSC) were characterized by means of the Ce K-edge and Zr K-edge XAFS. In order to investigate the relat...
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The complete structure of the cucumber (Cucumis sativus L.) chloroplast genome: Its composition and comparative analysis
The complete nucleotide sequence of the cucumber (C. sativus L. var. Borszczagowski) chloroplast genome has been determined. The genome is composed of 155,293 bp containing a pair of inverted repeats of 25,191 bp...
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Complete nucleotide sequence of the freshwater unicellular cyanobacterium Synechococcus elongatus PCC 6301 chromosome: gene content and organization
The entire genome of the unicellular cyanobacterium Synechococcus elongatus PCC 6301 (formerly Anacystis nidulans Berkeley strain 6301) was sequenced. The genome consisted of a circular chromosome 2,696,255 bp lo...
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The 2005 version of the chloroplast DNA sequence from tobacco (Nicotiana tabacum)
The complete nucleotide sequence of tobacco chloroplast DNA was first determined in 1986, and then its updated gene map was reported in 1998. During the course of sequencing the chloroplast DNA ofNicotiana sylves...
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Comparative NO x reduction behavior of Pt, Pd, and Rh supported catalysts in simulated exhaust gases as a function of oxygen concentration
NO x reduction activity on Pt and Pd catalysts had a maximum for S value as stoichiometry number at a fixed temperature, and the S value at the maximum NO x ...
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Molecular cloning, expression and characterization of three distinctive genes encoding methionine aminopeptidases in cyanobacterium Synechocystis sp. strain PCC6803
Methionine aminopeptidase, known to be encoded by single genes in prokaryotes, is a cobalt-dependent enzyme that catalyzes the removal of N-terminal methionine residues from nascent polypeptides. Three ORFs en...
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History of chloroplast genomics
The presence of chloroplast DNA was established in 1963. With the development of recombinant DNA technologies, chloroplast DNA was selected as one of the first candidates for genome sequencing. The first physi...
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Oxygen Storage Materials for Automotive Catalysts: Ceria-Zirconia Solid Solutions
This paper reviews progress in the development of oxygen storage materials for automotive exhaust catalysts. The research was mainly conducted as a study and development exercise in the author's laboratory in ...
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Plant 7SL RNA and tRNATyr genes with inserted antisense sequences are efficiently expressed in an in vitro transcription system from Nicotiana tabacum cells
RNA polymerase III-driven cassettes for the expression of antisense RNAs and ribozymes have recently attracted much attention because (1) pol III genes are transcribed abundantly in all kinds of tissues and (2...
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Comparative Analysis of RNA Editing Sites in Higher Plant Chloroplasts
Transcripts of land plant chloroplast genomes undergo C-to-U RNA editing. Systematic search disclosed 31 editing sites in tobacco, 27 in maize, and 21 in rice. Based on these identified sites, potential editi...
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The genomics of land plant chloroplasts: Gene content and alteration of genomic information by RNA editing
The entire nucleotide sequence of the chloroplast genome has been determined from 12 land plants. The gene content and arrangement are relatively uniform from species to species, and the genome contains an ave...
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Effect of Ba Addition on Catalytic Activity of Pt and Rh Catalysts Loaded on γ-Alumina
The catalytic activity of Pt catalyst loaded on γ-alumina was improved by Ba addition in simulated automotive exhaust gases. On the other hand, the result of Rh catalyst was the opposite. From the results of t...
