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Article
A resource of targeted mutant mouse lines for 5,061 genes
The International Mouse Phenoty** Consortium reports the generation of new mouse mutant strains for more than 5,000 genes, including 2,850 novel null, 2,987 novel conditional-ready and 4,433 novel reporter a...
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Article
Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics
Steve Brown and colleagues report an analysis of 20 phenoty** tests, including 413 data parameters, across 449 mutant mouse alleles. They identify widespread pleiotropy and assign putative functions to genes...