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Article
Open AccessComparison of solution-based exome capture methods for next generation sequencing
Techniques enabling targeted re-sequencing of the protein coding sequences of the human genome on next generation sequencing instruments are of great interest. We conducted a systematic comparison of the solut...
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Article
Open AccessTaME-seq: An efficient sequencing approach for characterisation of HPV genomic variability and chromosomal integration
HPV genomic variability and chromosomal integration are important in the HPV-induced carcinogenic process. To uncover these genomic events in an HPV infection, we have developed an innovative and cost-effectiv...
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Article
Open AccessExamining the effect of mitochondrial DNA variants on blood pressure in two Finnish cohorts
High blood pressure (BP) is a major risk factor for many noncommunicable diseases. The effect of mitochondrial DNA single-nucleotide polymorphisms (mtSNPs) on BP is less known than that of nuclear SNPs. We inv...