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    Article

    Non-viral liposomal keratinocyte growth factor (KGF) cDNA gene transfer improves dermal and epidermal regeneration through stimulation of epithelial and mesenchymal factors

    Keratinocyte growth factor (KGF) stimulates epithelial cell differentiation and proliferation, which are of major importance for wound healing. Local protein administration, however, has been shown to be ineff...

    MG Jeschke, G Richter, F Höfstädter, DN Herndon, J-R Perez-Polo, K-W Jauch in Gene Therapy (2002)

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    Article

    Therapeutic success and efficacy of nonviral liposomal cDNA gene transfer to the skin in vivo is dose dependent

    It is well documented that responses to growth factor treatment typically display bell-shaped dose responses that can significantly affect efficacy. Here we tested the hypothesis that nonviral liposomal gene d...

    MG Jeschke, G Richter, DN Herndon, EK Geissler, M Hartl, F Hofstätter… in Gene Therapy (2001)