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  1. Article

    Open Access

    An efficiency analysis of high-order combinations of gene–gene interactions using multifactor-dimensionality reduction

    Multifactor dimensionality reduction (MDR) is widely used to analyze interactions of genes to determine the complex relationship between diseases and polymorphisms in humans. However, the astronomical number o...

    Cheng-Hong Yang, Yu-Da Lin, Cheng-San Yang, Li-Yeh Chuang in BMC Genomics (2015)

  2. Article

    Open Access

    CpGPAP: CpG island predictor analysis platform

    Genomic islands play an important role in medical, methylation and biological studies. To explore the region, we propose a CpG islands prediction analysis platform for genome sequence exploration (CpGPAP).

    Li-Yeh Chuang, Cheng-Huei Yang, Ming-Cheng Lin, Cheng-Hong Yang in BMC Genetics (2012)

  3. Article

    Open Access

    LD2SN**: linkage disequilibrium plotter and RFLP enzyme mining for tag SNPs

    Linkage disequilibrium (LD) map** is commonly used to evaluate markers for genome-wide association studies. Most types of LD software focus strictly on LD analysis and visualization, but lack supporting serv...

    Hsueh-Wei Chang, Li-Yeh Chuang, Yan-Jhu Chang, Yu-Huei Cheng, Yu-Chen Hung in BMC Genetics (2009)

  4. Article

    Open Access

    SNP-RFL**: restriction enzyme mining for SNPs in genomes

    The restriction fragment length polymorphism (RFLP) is a common laboratory method for the genoty** of single nucleotide polymorphisms (SNPs). Here, we describe a web-based software, named SNP-RFL**, which ...

    Hsueh-Wei Chang, Cheng-Hong Yang, Phei-Lang Chang, Yu-Huei Cheng in BMC Genomics (2006)