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Article
Open AccessChromosome-level genome assembly of Helwingia omeiensis: the first genome in the family Helwingiaceae
Helwingia, a shrub of the monotypic cosmopolitan family Helwingiaceae, is distinguished by its inflorescence, in which flowers are borne on the midrib of the leaf—a trait not commonly observed in related plant fa...
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Article
The development and validation of a prediction model for imminent vertebral osteoporotic fracture in postmenopausal women
This study aimed to develop and validate a new model that focused on the risk of imminent vertebral fractures in women with osteoporosis.
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Article
The effect of digitalization on urban green total factor productivity: empirical evidence from China
The continuous progress of digital technology is having a profound impact on the course of sustainable development. Within this framework, the push towards digital transformation is anticipated to shape the ad...
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Article
Response of gut microbiota, antioxidation, and disease resistance to Pacific shrimp fed distiller’s dried grains with solubles replaced soybean meal
This experiment aimed to examine the potential of distiller’s dried grains with solubles (DDGS) meal as a substitute for soybean meal (SBM) in the Pacific shrimp diet. The study aimed to investigate how DDGS a...
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Article
Cell-nanocarrier drug delivery system: a promising strategy for cancer therapy
Tumor targeting has been a great challenge for drug delivery systems. A number of nanotechnology-derived drug carriers have been developed for cancer treatment to improve efficacy and biocompatibility. Among t...
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Article
Open AccessLaparoscopic versus laparotomic surgical treatment in apparent stage I ovarian cancer: a multi-center retrospective cohort study
Laparoscopic treatment shows non-inferior survival outcomes and better surgical outcomes in apparent stage I ovarian cancer (OC) in some studies but has not been well defined.
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Article
Open AccessA Population-Based Outcome-Wide Association Study of the Comorbidities and Sequelae Following COVID-19 Infection
Immense attention has been given to the outcome of COVID-19 infection. However, comprehensive studies based on large populational cohort with long-term follow-up are still lacking. This study aimed to investig...
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Open AccessResting-state functional connectivity of the cerebellum-cerebrum in older women with depressive symptoms
Although there has been much neurobiological research on major depressive disorder, research on the neurological function of depressive symptoms (DS) or subclinical depression is still scarce, especially in ol...
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Article
Open AccessmRNA-LNP vaccination-based immunotherapy augments CD8+ T cell responses against HPV-positive oropharyngeal cancer
Although mRNA vaccines are known as potent activators of antigen-specific immune responses against infectious diseases, limited understanding of how they drive the functional commitment of CD8+ T cells in tumor m...
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Article
Diacylated anthocyanins from purple sweet potato (Ipomoea batatas L.) attenuate hyperglycemia and hyperuricemia in mice induced by a high-fructose/high-fat diet
Studies have shown that targeting xanthine oxidase (XO) can be a feasible treatment for fructose-induced hyperuricemia and hyperglycemia. This study aimed to evaluate the dual regulatory effects and molecular ...
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Article
Open AccessEndoscopic submucosal dissection training: evaluation of an ex vivo training model with continuous perfusion (ETM-CP) for hands-on teaching and training in China
The existing ex vivo models of endoscopic submucosal dissection (ESD) cannot simulate intraoperative hemorrhage well. We aimed to establish an ESD training method by applying an ex vivo training model with con...
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Article
Changing temporal and spatial patterns of methane emission from rivers by reservoir dams: a review
Dams built on rivers can bring economic benefits to local production and are considered to be environmentally friendly. However, in recent years, many researchers found that the establishment of dams has creat...
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Article
Open AccessHaplotype-resolved genomes of two buckwheat crops provide insights into their contrasted rutin concentrations and reproductive systems
Two widely cultivated annual buckwheat crops, Fagopyrum esculentum and F. tataricum, differ from each other in both rutin concentration and reproductive system. However, the underlying genetic mechanisms remain p...
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Article
Open AccessA high-quality chromosome-level Eutrema salsugineum genome, an extremophile plant model
Eutrema salsugineum (2n = 14), a halophyte in the family Brassicaceae, is an attractive model to study abiotic stress tolerance in plants. Two versions of E. salsugineum genomes that previously reported were base...
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Article
Open AccessCyanidin-3-glucoside inhibits ferroptosis in renal tubular cells after ischemia/reperfusion injury via the AMPK pathway
Ferroptosis, which is characterized by lipid peroxidation and iron accumulation, is closely associated with the pathogenesis of acute renal injury (AKI). Cyanidin-3-glucoside (C3G), a typical flavonoid that ha...
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Article
Open AccessMeta-analysis of the relationship between bullying and depressive symptoms in children and adolescents
Childhood and adolescence are critical periods for physical and mental development; thus, they are high-risk periods for the occurrence of mental disorders. The purpose of this study was to systematically eval...
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Article
CO2 emissions are first aggravated and then alleviated with economic growth in China: a new multidimensional EKC analysis
CO2 emissions have become a topical issue worldwide, but few studies have considered the spatial effect of income on carbon emissions and explored the relationship between CO2 emissions and income by establishing...
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Article
Flower-like WS2 grown in nitrogen-doped CMK-3 with improved microwave absorbing performance
Flower-like WS2/N-CMK-3 hybrid materials were obtained by a facile one-step hydrothermal method. Due to the unique structure formed by the growth of WS2 petals on nitrogen-doped CMK-3 interlocking conductive netw...
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Article
1.7 kV normally-off p-GaN gate high-electron-mobility transistors on a semi-insulating SiC substrate
A study of 1.7 kV normally-off p-GaN gate high-electron-mobility transistors (HEMTs) on SiC substrates is presented. The fabricated p-GaN HEMT with a gate-drain spacing LGD = 5 µm exhibited a threshold voltage of...
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Article
Open AccessTranscriptome analysis reveals the high temperature induced damage is a significant factor affecting the osmotic function of gill tissue in Siberian sturgeon (Acipenser baerii)
Maintaining osmotic equilibrium plays an important role in the survival of cold-water fishes. Heat stress has been proven to reduce the activity of Na+/K+-ATPase in the gill tissue, leading to destruction of the ...