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  1. Article

    Open Access

    Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19

    A novel coronavirus, SARS-CoV-2, has been identified as the causative agent of the current COVID-19 pandemic. Animal models, and in particular non-human primates, are essential to understand the pathogenesis o...

    Francisco J. Salguero, Andrew D. White, Gillian S. Slack in Nature Communications (2021)

  2. Article

    Open Access

    Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity

    There is a vital need for authentic COVID-19 animal models to enable the pre-clinical evaluation of candidate vaccines and therapeutics. Here we report a dose titration study of SARS-CoV-2 in the ferret model....

    Kathryn A. Ryan, Kevin R. Bewley, Susan A. Fotheringham in Nature Communications (2021)

  3. Article

    Open Access

    Development of immunohistochemistry and in situ hybridisation for the detection of SARS-CoV and SARS-CoV-2 in formalin-fixed paraffin-embedded specimens

    The rapid emergence of SARS-CoV-2, the causative agent of COVID-19, and its dissemination globally has caused an unprecedented strain on public health. Animal models are urgently being developed for SARS-CoV-2...

    Fabian Z. X. Lean, Mart M. Lamers, Samuel P. Smith, Rebecca Shipley in Scientific Reports (2020)