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  1. No Access

    Article

    Uridine 5′-Diphospho-glucuronosyltransferase 1A3 (UGT1A3) Prediction of Hepatic Clearance of Organic Anion Transporting Polypeptide 1B3 (OATP1B3) Substrate Telmisartan by Glucuronidation Using In Vitro–In Vivo Extrapolation (IVIVE)

    The prediction of pharmacokinetic parameters for drugs metabolised by cytochrome P450 enzymes has been the subject of active research for many years, while the application of in vitro–in vivo extrapolation (IV...

    Ewelina Gabor-Worwa, Anna Kowal-Chwast… in European Journal of Drug Metabolism and Ph… (2024)

  2. Article

    Open Access

    Alterations in arginine and energy metabolism, structural and signalling lipids in metastatic breast cancer in mice detected in plasma by targeted metabolomics and lipidomics

    The early detection of metastasis based on biomarkers in plasma may improve cancer prognosis and guide treatment. The aim of this work was to characterize alterations in metabolites of the arginine pathway, en...

    Kamil Kus, Agnieszka Kij, Agnieszka Zakrzewska, Agnieszka Jasztal… in Breast Cancer Research (2018)

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