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Passion and commensurability: both are needed for a concurrence of surgery and research
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Exzellenzinitiative und Hochschulchirurgie
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Targeting the vasculature of visceral tumors: novel insights and treatment perspectives
Angiogenesis, the formation of new blood vessels from the endothelium of the existing vasculature, describes a crucial process in tumor growth, disease progression, and metastasis. Therefore, the upcoming stra...
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Long-term outcome after multivisceral and tumor/vascular resection in patients with soft tissue sarcoma
Soft tissue sarcomas (STS) are rare tumors. General treatment is difficult while multimodality treatment strategies are more and more common. In these strategies, surgical resection of the primary tumor is ess...
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Article
Influence of surgical trauma on the mRNA expression of sex hormone receptors in PBMCs in male and female patients
Gender-specific immune responses have been found after trauma-hemorrhage. Male and female sex hormones seem to be responsible for this gender dimorphism. Alterations in sex hormone receptor expression in mice ...
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Depressed T cell-derived IFN-γ following trauma-hemorrhage: a potential mechanism for diminished APC responses
Prolonged immunosuppression has been demonstrated after trauma-hemorrhage resulting in an increased susceptibility to sepsis. The contribution of antigen-presenting cells (APC) vs T cells to this diminished im...
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Angiogenesis in cancer: molecular mechanisms, clinical impact
Angiogenesis, the formation of new blood vessels from the endothelium of the existing vasculature, is fundamental in tumor growth, progression, and metastasis. Inhibiting tumor angiogenesis is a promising stra...
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Lower gastrointestinal bleeding: therapeutic strategies, surgical techniques and results
Lower gastrointestinal bleeding (LGIB) is normally treated conservatively or by noninvasive techniques. Emergency operations are only necessary when patients with severe hemorrhage cannot be stabilized by eme...
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Pankreaskarzinom — Bedeutung der Laparoskopie und der intraoperativen Spülzytologie für das perioperative Staging
Grundlagen: Operabilität bei Pankreaskarzinom erfordert auch heute noch trotz sensitiver Diagnostik häufig eine Staging-Laparotomie.
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Thrombembolektomie mit dem Fogarty-Katheter bei akuter Ischämie der oberen Extremitäten
Die Analyse und Nachuntersuchung von 220 Patienten mit einem akuten Arterienverschluß der oberen Extremität, bei denen 251 Thrombembolektomien mit dem Fogarty-Katheter durchgeführt wurden, ergab eine allgemein...
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Article
Auftreten maligner Weichgewebetumore (Sarkome) nach vorangegangener Srahlentherapie
The causal agent for sarcomas is mostly unknown. Unlike solid epithelial carcinomas, the correlation to the exposition to carcinogenic agents is unknown. Besides hereditary neurofibromatosis (“Recklinghausen”)...
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Postaggressionsstoffwechsel und Periduralanästhesie: Kataboliebeeinflussung durch Narkoseverfahren?
Postoperative catabolic state of metabolism represents a danger for patients in regard to protein degradation. As postoperative nutrition seems already quite optimal, we examined if anaesthesia, predominantly ...
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Article
353. Der Muskelstoffwechsel unter dem Einfluß von Fettinfusionen
In 12 volunteers and in 15 patients recovering from abdominal surgery, we investigated the effect of a fat infusion containing middle-chain triglyceride (MCT) or long-chain triglycerides (LCT) on skeletal musc...