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  1. Article

    Open Access

    Chromosome-level assembly reveals extensive rearrangement in saker falcon and budgerigar, but not ostrich, genomes

    The number of de novo genome sequence assemblies is increasing exponentially; however, relatively few contain one scaffold/contig per chromosome. Such assemblies are essential for studies of genotype-to-phenot...

    Rebecca E O’Connor, Marta Farré, Sunitha Joseph, Joana Damas in Genome Biology (2018)

  2. Article

    Open Access

    Reconstruction of avian ancestral karyotypes reveals differences in the evolutionary history of macro- and microchromosomes

    Reconstruction of ancestral karyotypes is critical for our understanding of genome evolution, allowing for the identification of the gross changes that shaped extant genomes. The identification of such changes...

    Joana Damas, Jaebum Kim, Marta Farré, Darren K Griffin, Denis M Larkin in Genome Biology (2018)

  3. Article

    Open Access

    Association of G-quadruplex forming sequences with human mtDNA deletion breakpoints

    Mitochondrial DNA (mtDNA) deletions cause disease and accumulate during aging, yet our understanding of the molecular mechanisms underlying their formation remains rudimentary. Guanine-quadruplex (GQ) DNA stru...

    Dawei W Dong, Filipe Pereira, Steven P Barrett, Jill E Kolesar, Kajia Cao in BMC Genomics (2014)