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Correction: Corrigenda: MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
Nat. Cell Biol. 14, 1336–1343 (2012); published online 25 November 2012; corrected after print 10 June 2015 In the version of this Letter originally published, a key funding source was omitted from the Acknowl...
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Article
Open AccessAssociation of G-quadruplex forming sequences with human mtDNA deletion breakpoints
Mitochondrial DNA (mtDNA) deletions cause disease and accumulate during aging, yet our understanding of the molecular mechanisms underlying their formation remains rudimentary. Guanine-quadruplex (GQ) DNA stru...
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Article
Erratum: MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
Nat. Cell Biol. 14, 1336–1343 (2012); published online 25th November 2012; corrected online 30th November 2012 In the version of this Letter that was originally published, the affiliation of Jordi Molgó was er...
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Article
MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
The mitochondrial calcium uniporter (MCU) mediates calcium uptake by mitochondria and thus regulates cellular bioenergetics, but how MCU activity is modulated is not fully understood. Madesh, Foskett and colle...
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Article
Mutation in TACO1, encoding a translational activator of COX I, results in cytochrome c oxidase deficiency and late-onset Leigh syndrome
Eric Shoubridge and colleagues report the identification of a mutation in the CCDC44 gene that is causal in a Leigh syndrome pedigree. The CCDC44 gene product, TACO1, is involved in mitochondrial translation and ...