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  1. No Access

    Article

    mTORC1/rpS6 and mTORC2/PKC regulate spermatogenesis through Arp3-mediated actin microfilament organization in Eriocheir sinensis

    Mammalian target of rapamycin (mTOR) is a crucial signaling protein regulating a range of cellular events. Numerous studies have reported that the mTOR pathway is related to spermatogenesis in mammals. However...

    Zhen-Fang Li, Hong-Yu Qi, Jia-Ming Wang, Zhan Zhao, Fu-Qing Tan… in Cell and Tissue Research (2023)

  2. No Access

    Article

    mTORC1/C2 regulate spermatogenesis in Eriocheir sinensis via alterations in the actin filament network and cell junctions

    Spermatogenesis is a finely regulated process of germ cell proliferation and differentiation that leads to the production of sperm in seminiferous tubules. Although the mammalian target of rapamycin (mTOR) sig...

    Zhen-Fang Li, Shuang-Li Hao, Lan-Min Wang, Hong-Yu Qi… in Cell and Tissue Research (2022)

  3. Article

    Open Access

    Analyses of distribution and dosimetry of brain metastases in small cell lung cancer with relation to the neural stem cell regions: feasibility of sparing the hippocampus in prophylactic cranial irradiation

    This work aims to assess the feasibility of selectively sparing the hippocampus during prophylactic cranial irradiation (PCI) for small cell lung cancer (SCLC).

    Lei Zhao, Yan Shen, **-Dong Guo, Heng-Le Gu, Wen Yu, Jia-Ming Wang… in Radiation Oncology (2017)

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  4. No Access

    Article

    Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats

    Spontaneously hypertensive rats (SHR) display several features of the human insulin-resistance syndromes. Cd36 deficiency is genetically linked to insulin resistance in SHR. We show that transgenic expression ...

    Michal Pravenec, Vladimir Landa, Vaclav Zidek, Alena Musilova… in Nature Genetics (2001)

  5. No Access

    Article

    Linkage of 11β-hydroxylase mutations with altered steroid biosynthesis and blood pressure in the Dahl rat

    In Dahl salt-hypertension sensitive (S) and resistant (R) strains fed a high NaCI diet, 11β-hydroxylase polymorphisms cosegregate with the adrenal capacity to synthesize 18-hydroxy-11-deoxycorticosterone (18-O...

    George T. Cicila, John P. Rapp, Jia-Ming Wang, Elizabeth St. Lezin… in Nature Genetics (1993)