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558 Result(s)
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Article
Intact 5-HT2A Receptor Exons and the Adjoining Intron Regions in Schizophrenia
Genes that regulate serotonergic (5-HT) systems may underlie the etiology of schizophrenia. In this study the gene encoding the 5-HT2A receptor in schizophrenics and healthy controls was examined. First, we seque...
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Correction: Prediction of bone density from vitamin D raceptor alleles
Nature 367, 284-287 (1994) .... In order to expand our original observations of a relationship between bone density and vitamin D receptor (VDR) genotype and to examine other genes potentially involved in bone...
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Article
A rod-type creepmeter for measurement of displacement in active fault zone
A creepmeter has been developed to monitor gradual displacements of near-surface movement in an active fault zone. This rod-type creepmeter is a robust, low-cost instrument that is simple to construct and inst...
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Article
Open AccessImproved residue contact prediction using support vector machines and a large feature set
Predicting protein residue-residue contacts is an important 2D prediction task. It is useful for ab initio structure prediction and understanding protein folding. In spite of steady progress over the past decade,...
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Open AccessA multi-template combination algorithm for protein comparative modeling
Multiple protein templates are commonly used in manual protein structure prediction. However, few automated algorithms of selecting and combining multiple templates are available.
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Open AccessHMMEditor: a visual editing tool for profile hidden Markov model
Profile Hidden Markov Model (HMM) is a powerful statistical model to represent a family of DNA, RNA, and protein sequences. Profile HMM has been widely used in bioinformatics research such as sequence alignmen...
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Open AccessProtein disorder prediction at multiple levels of sensitivity and specificity
Many protein regions and some entire proteins have no definite tertiary structure, existing instead as dynamic, disorder ensembles under different physiochemical circumstances. Identification of these protein ...
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Open AccessCoseismic displacements and slip distribution from GPS and leveling observations for the 2006 Peinan earthquake (Mw 6.1) in southeastern Taiwan
Since 2001, we have set up a dense geodetic network with 52 campaign-mode GPS sites and seven continuously recording GPS stations as well as six leveling routes in the Taitung area, Taiwan. Our aim was to bett...
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Influence of 2008 Wenchuan earthquake on earthquake occurrence trend of active faults in Sichuan-Yunnan region
The Wenchuan earthquake coseismic deformation field is inferred from the coseismic dislocation data based on a 3-D geometric model of the active faults in Sichuan-Yunnan region. Then the potential dislocation ...
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Article
Open AccessPreDisorder: ab initio sequence-based prediction of protein disordered regions
Disordered regions are segments of the protein chain which do not adopt stable structures. Such segments are often of interest because they have a close relationship with protein expression and functionality. ...
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Article
Open AccessGenome sequence of the palaeopolyploid soybean
Soybean (Glycine max) is one of the most important crop plants for seed protein and oil content, and for its capacity to fix atmospheric nitrogen through symbioses with soil-borne microorganisms. We sequenced the...
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Article
Open AccessSoyDB: a knowledge database of soybean transcription factors
Transcription factors play the crucial rule of regulating gene expression and influence almost all biological processes. Systematically identifying and annotating transcription factors can greatly aid further ...
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Article
Open AccessDecreased NPC1L1 expression in the liver from Chinese female gallstone patients
Cholesterol gallstone disease is a very common disease in both industrialized and develo** countries. Many studies have found that cholesterol gallstones are more common in women than men. The molecular mech...
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Article
Open AccessSeqRate: sequence-based protein folding type classification and rates prediction
Protein folding rate is an important property of a protein. Predicting protein folding rate is useful for understanding protein folding process and guiding protein design. Most previous methods of predicting p...
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Erratum: Genome sequence of the palaeopolyploid soybean
Nature 463, 178–183 (2010) During resubmission of this work, a paper was published1 that used a comparative genomics approach between soybean and maize to show that a single-base mutation in chromosome 19 acco...
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Development of a large-scale isolation chamber system for the safe and humane care of medium-sized laboratory animals harboring infectious diseases
The close phylogenetic relationship between humans and non-human primates makes non-human primates an irreplaceable model for the study of human infectious diseases. In this study, we describe the development ...
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Article
Open AccessGeochemistry of soil gas in the seismic fault zone produced by the Wenchuan Ms 8.0 earthquake, southwestern China
The spatio-temporal variations of soil gas in the seismic fault zone produced by the 12 May 2008 Wenchuan Ms 8.0 earthquake were investigated based on the field measurements of soil gas concentrations after the m...
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Article
Open AccessDoBo: Protein domain boundary prediction by integrating evolutionary signals and machine learning
Accurate identification of protein domain boundaries is useful for protein structure determination and prediction. However, predicting protein domain boundaries from a sequence is still very challenging and la...
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Article
Open AccessMammal Cells Double Their Total RNAs against Diabetes, Ischemia Reperfusion and Malaria-Induced Oxidative Stress
Total cellular RNA level is stable usually, although it may increase gradually during growth or decrease gradually under certain stressors. However, we found that mammal cell RNAs could be doubled within 24 h ...
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Open AccessSalicylic acid and ethylene signaling pathways are involved in production of rice trypsin proteinase inhibitors induced by the leaf folder Cnaphalocrocis medinalis (Guenée)
The roles of signaling pathways in the production of trypsin proteinase inhibitors (TrypPIs) in rice infested by the leaf folder (LF) Cnaphalocrocis medinalis were studied. Infestation by LF increased TrypPI leve...