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  1. Article

    Open Access

    An Image Turing Test on Realistic Gastroscopy Images Generated by Using the Progressive Growing of Generative Adversarial Networks

    Generative adversarial networks (GAN) in medicine are valuable techniques for augmenting unbalanced rare data, anomaly detection, and avoiding patient privacy issues. However, there were limits to generating h...

    Keewon Shin, Jung Su Lee, Ji Young Lee, Hyunsu Lee in Journal of Digital Imaging (2023)

  2. Article

    Open Access

    Integrative modeling of tumor genomes and epigenomes for enhanced cancer diagnosis by cell-free DNA

    Multi-cancer early detection remains a key challenge in cell-free DNA (cfDNA)-based liquid biopsy. Here, we perform cfDNA whole-genome sequencing to generate two test datasets covering 2125 patient samples of ...

    Mingyun Bae, Gyuhee Kim, Tae-Rim Lee, ** Mo Ahn, Hyunwook Park in Nature Communications (2023)

  3. Article

    Open Access

    Clinical outcomes of colonoscopic polypectomy with strategic surveillance colonoscopies in patients with 10 or more polyps

    The clinical usefulness of repeat colonoscopic polypectomy in patients with numerous polyps has not been sufficiently determined. We aimed to analyze the clinical outcomes of colonoscopic polypectomy with surv...

    ** Hwa Park, Seung Wook Hong, Sung Wook Hwang, Sang Hyoung Park in Scientific Reports (2023)

  4. No Access

    Article

    Oncological outcomes according to the treatment modality based on the size of rectal neuroendocrine tumors: a single-center retrospective study

    Owing to an increased number of colonoscopy screenings, the incidence of diagnosed rectal neuroendocrine tumors (NETs) has also increased. Tumor size is one of the most frequently regarded factors when selecti...

    Jimin Son, In Ja Park, Dong-Hoon Yang, Jisup Kim, Kyoung-Jo Kim in Surgical Endoscopy (2022)

  5. No Access

    Article

    Chronic Viral Hepatitis Is Associated with Colorectal Neoplasia: A Systematic Review and Meta-Analysis

    Chronic viral hepatitis is associated with a wide range of extrahepatic diseases; however, evidence on a link between chronic viral hepatitis and colorectal neoplasia is still lacking.

    Seung Wook Hong, Won-Mook Choi, Ha Won Hwang in Digestive Diseases and Sciences (2021)

  6. Article

    Open Access

    Risk and characteristics of tuberculosis after anti-tumor necrosis factor therapy for inflammatory bowel disease: a hospital-based cohort study from Korea

    Anti-tumor necrosis factor (TNF) treatment for inflammatory bowel disease (IBD) increases the risk of tuberculosis (TB) infection. In the present study, we analyzed the clinical characteristics and risks of TB...

    Jae Yong Lee, Kyunghwan Oh, Hee Seung Hong, Kyuwon Kim in BMC Gastroenterology (2021)

  7. No Access

    Article

    The Clinical Significance of Anastomotic Ulcers After Ileocolic Resection to Predict Postoperative Recurrence of Crohn’s Disease

    The Rutgeerts score is used to predict postoperative recurrence in CD patients after ileocolic resection and is primarily based on endoscopic findings at the neoterminal ileum. However, the optimal assessment ...

    ** Yong Kim, Sang Hyoung Park, Jae Cheol Park in Digestive Diseases and Sciences (2021)

  8. No Access

    Article

    Usefulness of narrow-band imaging for the detection of remnant sessile-serrated adenoma (SSA) tissue after endoscopic resection: the KASID multicenter study

    A sessile-serrated adenoma (SSA) has a high risk for incomplete resection. Little is known regarding how to immediately detect remnant SSA tissue after endoscopic resection. We investigated the usefulness of n...

    Yunho Jung, Jung Rock Moon, Seong Ran Jeon, Jae Myung Cha in Surgical Endoscopy (2021)

  9. Article

    Open Access

    Biomolecular imaging of colorectal tumor lesions using a FITC-labeled scFv-Cκ fragment antibody

    For the sensitive diagnosis of colorectal cancer lesions, advanced molecular imaging techniques using cancer-specific targets have emerged. However, issues regarding the clearance of unbound probes and immunog...

    Hyung Il Kim, **hyeon Kim, Hyori Kim, Hyeri Lee, Yong Sik Yoon in Scientific Reports (2021)

  10. Article

    Open Access

    Anchoring the snare tip is a feasible endoscopic mucosal resection method for small rectal neuroendocrine tumors

    Small rectal neuroendocrine tumors (NETs) can be treated using cap-assisted endoscopic mucosal resection (EMR-C), which requires additional effort to apply a dedicated cap and snare. We aimed to evaluate the f...

    Jeongseok Kim, Jisup Kim, Eun Hye Oh, Nam Seok Ham, Sung Wook Hwang in Scientific Reports (2021)

  11. Article

    Open Access

    Endoscopic features and clinical outcomes of cytomegalovirus gastroenterocolitis in immunocompetent patients

    We aimed to investigate the endoscopic features and clinical course of CMV gastroenterocolitis in immunocompetent patients. We reviewed the medical records and endoscopic images of 86 immunocompetent patients ...

    Jiyoung Yoon, Junghwan Lee, Dae Sung Kim, ** Wook Lee in Scientific Reports (2021)

  12. Article

    Open Access

    Machine learning approach for differentiating cytomegalovirus esophagitis from herpes simplex virus esophagitis

    The endoscopic features between herpes simplex virus (HSV) and cytomegalovirus (CMV) esophagitis overlap significantly, and hence the differential diagnosis between HSV and CMV esophagitis is sometimes difficu...

    Jung Su Lee, Jihye Yun, Sungwon Ham, Hyunjung Park, Hyunsu Lee in Scientific Reports (2021)

  13. No Access

    Article

    Influence of Severe Vitamin D Deficiency on the Clinical Course of Inflammatory Bowel Disease

    Previous studies have shown vitamin D status to be associated with disease activity in patients with inflammatory bowel disease (IBD), but its influence on the clinical course of IBD has not been established.

    Nam Seok Ham, Sung Wook Hwang, Eun Hye Oh, Jeongseok Kim in Digestive Diseases and Sciences (2021)

  14. Article

    Open Access

    Risk of postpolypectomy bleeding in patients taking direct oral anticoagulants or clopidogrel

    The usage of direct oral anticoagulants (DOACs) to prevent and treat thromboembolic events is gradually increasing. We aimed to evaluate the outcomes of patients taking DOACs after polypectomy. We retrospectiv...

    Gwang-Un Kim, Sinwon Lee, Jaewon Choe, Sung Wook Hwang in Scientific Reports (2021)

  15. Article

    Open Access

    Prevalence and risk factors of bowel symptoms in Korean patients with ulcerative colitis in endoscopic remission: a retrospective study

    Many patients with ulcerative colitis (UC) in clinical remission frequently complain of bowel symptoms such as increased stool frequency (SF) and rectal bleeding (RB). However, studies on these patient-reporte...

    Kwangwoo Nam, Sang Hyoung Park, Jun Ho Oh, Ho-Su Lee, Soomin Noh in BMC Gastroenterology (2021)

  16. No Access

    Article

    Technical feasibility of a newly designed bendable forceps for difficult endoscopic tissue samplings (with video)

    Biopsies with conventional forceps beyond the operating range are difficult and cumbersome. Thus, we developed a new bendable forceps for improved access to gastrointestinal lesions and evaluated its technical...

    Dong Seok Lee, Ji Won Kim, Kook Lae Lee, Byeong Gwan Kim, Su Hwan Kim in Surgical Endoscopy (2020)

  17. No Access

    Article

    Tip-in versus conventional endoscopic mucosal resection for flat colorectal neoplasia 10 mm or larger in size

    A modified endoscopic mucosal resection (EMR) technique, Tip-in EMR, was recently introduced to enhance the complete resection of colorectal neoplasia (CRN). We aimed to evaluate the feasibility of Tip-in EMR ...

    Soo Min Noh, ** Yong Kim, Jae Cheol Park in International Journal of Colorectal Disease (2020)

  18. No Access

    Article

    Association Between Carotid Ultrasonography Findings and Colorectal Adenoma in Asymptomatic Adults

    Coexistence of colorectal neoplasia and atherosclerotic cardiovascular disease has been reported. Subclinical atherosclerosis can be evaluated noninvasively and easily by assessing carotid intima–media thickne...

    Jeongseok Kim, Ji Young Lee, Nam Seok Ham, Eun Hye Oh in Digestive Diseases and Sciences (2020)

  19. Article

    Open Access

    Real-time detection of colon polyps during colonoscopy using deep learning: systematic validation with four independent datasets

    We developed and validated a deep-learning algorithm for polyp detection. We used a YOLOv2 to develop the algorithm for automatic polyp detection on 8,075 images (503 polyps). We validated the algorithm using ...

    Ji Young Lee, **hoon Jeong, Eun Mi Song, Chunae Ha, Hyo Jeong Lee in Scientific Reports (2020)

  20. No Access

    Article

    Incidence and Outcomes of Perianal Disease in an Asian Population with Crohn’s Disease: A Nationwide Population-Based Study

    Little is known about the natural history of perianal fistulas in Asian populations with Crohn’s disease (CD).

    Eun Mi Song, Ho-Su Lee, Ye-Jee Kim, Eun Hye Oh in Digestive Diseases and Sciences (2020)

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