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  1. Article

    Open Access

    In vivo safety and biodistribution profile of Klotho-enhanced human urine-derived stem cells for clinical application

    Urine-derived stem cells (UDSCs) can be easily isolated from urine and possess excellent stem cell characteristics, making them a promising source for cell therapeutics. Due to their kidney origin specificity,...

    Sang-Heon Kim, Sung-Hoon Lee, Jeong-Ah **, Hyung-Joon So in Stem Cell Research & Therapy (2023)

  2. No Access

    Article

    Nano-characterizations of low-dimensional nanostructural materials

    Nondestructive nano-characterization methods were reviewed with respect to technical aspect and practicability. Micro-photoluminescence, cathodoluminscence and Raman spectroscopy with map** modes were invest...

    Hye-Won Seo, Jae-Ung Lee, Chan-Ho Yang in Journal of the Korean Physical Society (2022)

  3. No Access

    Article

    Coherent many-body exciton in van der Waals antiferromagnet NiPS3

    An exciton is the bosonic quasiparticle of electron–hole pairs bound by the Coulomb interaction1. Bose–Einstein condensation of this exciton state has long been the subject of speculation in various model systems

    Soonmin Kang, Kangwon Kim, Beom Hyun Kim, Jonghyeon Kim, Kyung Ik Sim in Nature (2020)

  4. Article

    Open Access

    Estrogen receptor α in T cells suppresses follicular helper T cell responses and prevents autoimmunity

    Estrogen receptor alpha (ERα) is a sex hormone nuclear receptor that regulates various physiological events, including the immune response. Although there have been some recent studies on ERα regarding subsets...

    Do-Hyun Kim, Hong-Jai Park, Hyeon-Soo Park in Experimental & Molecular Medicine (2019)

  5. Article

    Open Access

    Pathogenic function of bystander-activated memory-like CD4+ T cells in autoimmune encephalomyelitis

    T cells generate antigen-specific immune responses to their cognate antigen as a hallmark of adaptive immunity. Despite the importance of antigen-specific T cells, here we show that antigen non-related, bystan...

    Hong-Gyun Lee, Jae-Ung Lee, Do-Hyun Kim, Sangho Lim, Insoo Kang in Nature Communications (2019)

  6. Article

    Open Access

    Suppression of magnetic ordering in XXZ-type antiferromagnetic monolayer NiPS3

    How a certain ground state of complex physical systems emerges, especially in two-dimensional materials, is a fundamental question in condensed-matter physics. A particularly interesting case is systems belong...

    Kangwon Kim, Soo Yeon Lim, Jae-Ung Lee, Sungmin Lee, Tae Yun Kim in Nature Communications (2019)

  7. Article

    Open Access

    Strain-shear coupling in bilayer MoS2

    Layered materials such as graphite and transition metal dichalcogenides have extremely anisotropic mechanical properties owing to orders of magnitude difference between in-plane and out-of-plane interatomic in...

    Jae-Ung Lee, Sungjong Woo, Jaesung Park, Hee Chul Park in Nature Communications (2017)

  8. Article

    Open Access

    Gender-specific differences in PPARγ regulation of follicular helper T cell responses with estrogen

    Peroxisome proliferator-activated receptor gamma (PPARγ), a master regulator of adipocyte differentiation, has recently been connected with effector T cells, though its role is still not clear. Here, we invest...

    Hong-Jai Park, Hyeon-Soo Park, Jae-Ung Lee, Alfred L. M. Bothwell in Scientific Reports (2016)

  9. Article

    Open Access

    Excitation energy dependent Raman spectrum of MoSe2

    Raman investigation of MoSe2 was carried out with eight different excitation energies. Seven peaks, including E1g, A1g, E2g1 and A2u2 peaks are observed in the range of 100–400 cm−1. The phonon modes are assigned...

    Dahyun Nam, Jae-Ung Lee, Hyeonsik Cheong in Scientific Reports (2015)

  10. Article

    Open Access

    dNP2 is a blood–brain barrier-permeable peptide enabling ctCTLA-4 protein delivery to ameliorate experimental autoimmune encephalomyelitis

    Central nervous system (CNS)-infiltrating effector T cells play critical roles in the development and progression of multiple sclerosis (MS). However, current drugs for MS are very limited due to the difficult...

    Sangho Lim, Won-Ju Kim, Yeon-Ho Kim, Sohee Lee, Ja-Hyun Koo in Nature Communications (2015)

  11. Article

    Open Access

    Excitation Energy Dependent Raman Signatures of ABA- and ABC-stacked Few-layer Graphene

    The dependence of the Raman spectrum on the excitation energy has been investigated for ABA-and ABC- stacked few-layer graphene in order to establish the fingerprint of the stacking order and the number of lay...

    The An Nguyen, Jae-Ung Lee, Duhee Yoon, Hyeonsik Cheong in Scientific Reports (2014)

  12. Article

    Efficacy of losartan and carvedilol on central hemodynamics in hypertensives: a prospective, randomized, open, blinded end point, multicenter study

    Renin–angiotensin system (RAS) blockers have shown clinical outcomes superior to those of the beta (β)-blocker atenolol, despite similar reductions in the peripheral blood pressure (BP), perhaps because of dif...

    Eung Ju Kim, Woo-Hyuk Song, Jae Ung Lee, Mi-Seung Shin, Sahng Lee in Hypertension Research (2014)