19 Result(s)

Article

Lifeday coverage of oral anticoagulants and one-year relative survival in patients with atrial fibrillation: a population-based study in Estonia

Routine oral anticoagulation (OAC) is recommended for almost all high-risk patients with atrial fibrillation, yet registries show that OACs are still underused. Our aim was to study the lifeday coverage (LDC) ...

Priit Pauklin, Toomas Marandi, Mart Kals, Tiia Ainla… in BMC Cardiovascular Disorders (2023)

Article

Adherence to recommendations for secondary prevention medications after myocardial infarction in Estonia: comparison of real-world data from 2004 to 2005 and 2017 to 2018

Relatively high rates of adherence to myocardial infarction (MI) secondary prevention medications have been reported, but register-based, objective real-world data is scarce. We aimed to analyse adherence to g...

Piret Lõiveke, Toomas Marandi, Tiia Ainla, Krista Fischer… in BMC Cardiovascular Disorders (2021)

Article

Remote ischaemic preconditioning influences the levels of acylcarnitines in vascular surgery: a randomised clinical trial

Vascular surgery patients have reduced tissues` blood supply, which may lead to mitochondrial dysfunction and accumulation of acylcarnitines (ACs). It has been suggested that remote ischaemic preconditioning (...

Teele Kasepalu, Karl Kuusik, Urmas Lepner, Joel Starkopf… in Nutrition & Metabolism (2020)

Article

P55 Remote Ischaemic Preconditioning Reduces Cardiac Biomarkers During Vascular Surgery

The primary aim of this study was to evaluate the effects of remote ischaemic preconditioning (RIPC) on preventing the leakage of cardiac damage biomarkers in patients undergoing vascular surgery.

Teele Kepler, Karl Kuusik, Urmas Lepner, Joel Starkopf, Mihkel Zilmer… in Artery Research (2019)

Article

P48 Effects of Remote Ischaemic Preconditioning on Haemodynamic and Arterial Stiffness Parameters in Patients Undergoing Lower Limb Angiographic Procedure

Remote ischaemic preconditioning (RIPC) is a phenomenon that promotes protection of tissues and organs against ischaemia-reperfusion injury. RIPC has been shown to reduce myocardial and renal injury but its ef...

Karl Kuusik, Teele Kepler, Mihkel Zilmer, Jaan Eha, Mare Vähi… in Artery Research (2019)

Article

P65 Remote Ischaemic Preconditioning Reduces Kidney Injury in Vascular Surgery

Perioperative acute kidney injury has been found to occur in 12% of patients undergoing lower limb revascularisation (Arora et al., 2013). The aim of the current double-blinded, randomised and shamcontrolled p...

Teele Kepler, Karl Kuusik, Urmas Lepner, Joel Starkopf, Mihkel Zilmer… in Artery Research (2018)

Article

P77 Targeted Lipidomics of Arterial Stiffness and Hemodynamics in Atherosclerosis

This study examined relationships between lipidomic profile, arterial function and hemodynamics in coronary artery disease (CAD) patients, peripheral arterial disease (PAD) patients and healthy controls.

Kaido Paapstel, Jaak Kals, Jaan Eha, Kaspar Tootsi, Aigar Ottas… in Artery Research (2018)

Article

Benefit-Risk Assessment of Crataegus Extract WS 1442: An Evidence-Based Review

Preparations from Crataegus (hawthorn) have a long history in the treatment of heart failure. WS 1442 is a dry extract from hawthorn leaves with flowers (4–6.6:1), extraction solvent of ethanol 45% (w/w), adjuste...

Christian J. F. Holubarsch, Wilson S. Colucci… in American Journal of Cardiovascular Drugs (2018)

Article

Response to Aboyans, et al.: Estimation of pulse wave velocity in patients with peripheral artery disease: a word of caution

Maksim Zagura, Jaak Kals, Kaido Paapstel, Martin Serg… in Hypertension Research (2016)

Article

P3.12 Urinary Liver-Type Fatty Acid-Binding Protein is Associated with Aortic Stiffness in Male Coronary Artery Disease Patients

Urinary liver-type fatty acid-binding protein (L-FABP) is a promising diagnostic and prognostic biomarker for both acute and chronic kidney injury. Furthermore, this protein has been shown to possess antioxida...

Kaido Paapstel, Mihkel Zilmer, Jaan Eha, Kaspar Tootsi, Anneli Piir… in Artery Research (2015)

Article

Metabolomic signature of arterial stiffness in male patients with peripheral arterial disease

Arterial stiffness is an independent determinant of cardiovascular risk and a marker of subclinical organ damage. Metabolomics may facilitate identification of novel low-molecular cardiovascular risk factors. ...

Maksim Zagura, Jaak Kals, Kalle Kilk, Martin Serg, Priit Kampus… in Hypertension Research (2015)

Article

Improved treatment and prognosis after acute myocardial infarction in Estonia: cross-sectional study from a high risk country

The aim of the study was to explore trends in short- and long-term mortality after hospitalization for acute myocardial infarction (AMI) over the period 2001─2011 in Estonian secondary and tertiary care hospit...

Aet Saar, Toomas Marandi, Tiia Ainla, Krista Fischer… in BMC Cardiovascular Disorders (2015)

Article

Angiotensin II receptor blocker telmisartan attenuates aortic stiffening and remodelling in STZ-diabetic rats

Prevention or attenuation of diabetic vascular complications includes anti-hypertensive treatment with renin-angiotensin system inhibitors on account of their protective effects beyond blood pressure reduction...

Erik Salum, Mark Butlin, Jaak Kals, Mihkel Zilmer… in Diabetology & Metabolic Syndrome (2014)

Article

Structural and biochemical characteristics of arterial stiffness in patients with atherosclerosis and in healthy subjects

Arterial stiffness is an independent predictor of vascular morbidity and mortality in patients with atherosclerosis. Angiographic score (ASc) reflects severity of atherosclerosis in patients with peripheral ar...

Maksim Zagura, Jaak Kals, Martin Serg, Priit Kampus, Mihkel Zilmer… in Hypertension Research (2012)

Article

Sex-specific outcomes of diabetic patients with acute myocardial infarction who have undergone percutaneous coronary intervention: a register linkage study

The presence of diabetes mellitus poses a challenge in the treatment of patients with acute myocardial infarction (AMI). We aimed to evaluate the sex-specific outcomes of diabetic and non-diabetic patients wit...

Mai Blöndal, Tiia Ainla, Toomas Marandi, Aleksei Baburin… in Cardiovascular Diabetology (2012)

Article

Effect of vitamin D on aortic remodeling in streptozotocin-induced diabetes

Diabetes mellitus is associated with micro- and macrovascular complications and increased cardiovascular risk. Elevated levels of serum asymmetric dimethylarginine (ADMA) may be responsible for endothelial dys...

Erik Salum, Priit Kampus, Mihkel Zilmer, Jaan Eha… in Cardiovascular Diabetology (2012)

Article

Changes in treatment and mortality of acute myocardial infarction in Estonian tertiary and secondary care hospitals in 2001 and 2007

High quality care for acute myocardial infarction (AMI) improves patient outcomes. Still, AMI patients are treated in hospitals with unequal access to percutaneous coronary intervention. The study compares cha...

Mai Blöndal, Tiia Ainla, Toomas Marandi, Aleksei Baburin, Jaan Eha in BMC Research Notes (2012)