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  1. No Access

    Article

    L’organisation française en réseau de soins pour la prise en charge des sarcomes

    Les sarcomes sont des cancers rares et hétérogènes, dont la prise en charge est complexe et non optimale pour la majorité des patients. Les trois éléments clés de la prise en charge sont l’obtention d’un diagn...

    F. Ducimetière, J.-M. Coindre, F. Gouin, G. Du Bouexic de Pinieux, C. Chemin… in Oncologie (2016)

  2. No Access

    Article

    Frequencies of KIT and PDGFRA mutations in the MolecGIST prospective population-based study differ from those of advanced GISTs

    Gastrointestinal stromal tumors (GISTs) are the most common human sarcoma. Most of the data available on GISTs derive from retrospective studies of patients referred to oncology centers. The MolecGIST study so...

    J. F. Emile, S. Brahimi, J. M. Coindre, P. P. Bringuier, G. Monges… in Medical Oncology (2012)

  3. Article

    Aux origines de la maladie osseuse de Paget. Un nouveau cas néolithique dans le sud de la France

    Parmi les ossements recueillis dans une grotte sépulcrale du sud de la France, nous avons reconnu un cas de maladie de Paget polyostotique. La datation C14, après calibration, donne un âge d’environ 3350 ans avan...

    J. -P. Arnautou, J. Blondiaux… in Bulletins et mémoires de la Société d'anth… (2011)

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  4. Article

    Open Access

    High frequency of β-catenin heterozygous mutations in extra-abdominal fibromatosis: a potential molecular tool for disease management

    Fibromatosis comprises distinct clinical entities, including sporadic extra-abdominal fibromatosis, which have a high tendency for recurrence, even after adequate resection. There are no known molecular biomar...

    J Dômont, S Salas, L Lacroix, V Brouste, P Saulnier, P Terrier… in British Journal of Cancer (2010)

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  5. Article

    Open Access

    Prognosis and predictive value of KIT exon 11 deletion in GISTs

    KIT exon 11 mutations are observed in 60% of gastrointestinal stromal tumours (GIST). Exon 11 codes for residues Tyr568 and Tyr570, which play a major role in signal transduction and degradation of KIT. Our aim w...

    J-B Bachet, I Hostein, A Le Cesne, S Brahimi, A Beauchet… in British Journal of Cancer (2009)

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  6. No Access

    Article

    Intérêt des banques de tumeurs virtuelles annotées dans les sarcomes : expérience et projet du Groupe Sarcome Français et du réseau européen Conticanet

    Sarcomas are rare and various tumours likely to constitute an adequate model for collaborative studies of collected data and tumour samples. The French Sarcoma Group has created an “annotated virtual tumour ba...

    J. -M. Coindre in Oncologie (2008)

  7. No Access

    Article

    Standards, Options et Recommandations 2006. Prise en charge des patients adultes atteints de sarcome des tissus mous, de sarcome utérin ou de tumeur stromale gastro-intestinale

    La mise à jour des recommandations pour la pratique clinique (RPC) pour la prise en charge des patients atteints d’un sarcome des tissus mous a été élaborée par la Fédération nationale des centres de lutte con...

    B. -N. Bui, J. -Y. Blay, F. Bonichon, S. Bonvalot, A. Chevalier-Place… in Oncologie (2007)

  8. No Access

    Article

    Chirurgie des sarcomes des tissus mous des membres et de la paroi du tronc

    En 20 ans, le taux de contrôle local des sarcomes des tissus mous est passé d’environ 70 à 80 %, grâce entre autres aux progrès de la chirurgie. En dehors des centres spécialisés, la prise en charge des sarcom...

    E. Stöckle, J. -M. Coindre, L. Thomas, M. Bui, G. Kantor, M. Kind, B. -N. Bui in Oncologie (2007)

  9. No Access

    Article

    Tumeurs stromales du tube digestif (GIST)

    Les tumeurs stromales du tube digestif (GIST) sont des tumeurs mésenshymateuses malignes rares, liées à une mutation fonctionnelle de c-kit ou de PDGFα. La prise en charge et le pronostic de ces tumeurs ont ét...

    B. -N. Bui, E. Stöeckle, M. Kind, J. -M. Coindre in Oncologie (2007)

  10. No Access

    Article

    Intérêt et limites du grade histopronostique dans les sarcomes des tissus mous

    J.-M. Coindre in Oncologie (2006)

  11. Article

    Open Access

    DNA topoisomerase IIα expression and the response to primary chemotherapy in breast cancer

    The α isoform of Topoisomerase IIα (Topo IIα) is a proliferation marker as well as a target for several chemotherapeutic agents such as anthracyclines. In vitro studies have demonstrated the relationship between ...

    G MacGrogan, P Rudolph, I de Mascarel, L Mauriac, M Durand… in British Journal of Cancer (2003)

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  12. Article

    Open Access

    Summary of the Standards, Options and Recommendations for the management of patients with carcinoma of unknown primary site (2002)

    R Bugat, A Bataillard, T Lesimple, J J Voigt, S Culine… in British Journal of Cancer (2003)

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  13. No Access

    Article

    pS2 protein: a marker improving prediction of response to neoadjuvant tamoxifen in post-menopausal breast cancer patients

    Tamoxifen as sole initial therapy is gaining importance in the management of post-menopausal breast cancer patients. Age oestrogen (ER) and progesterone (PR) receptor status are accurately considered to select...

    I Soubeyran, N Quénel, J-M Coindre, F Bonichon, M Durand… in British Journal of Cancer (1996)

  14. No Access

    Article

    Variation of hormonal receptor, pS2, c-erbB-2 and GSTπ contents in breast carcinomas under tamoxifen: a study of 74 cases

    Seventy-four post menopausal patients with primary non-metastatic invasive ductal carcinomas of the breast were first treated with tamoxifen alone (30 mg p.o. daily) for 5 months. To study changes induced by t...

    I Soubeyran, N Quénel, L Mauriac, M Durand, F Bonichon… in British Journal of Cancer (1996)

  15. No Access

    Article

    Abstracts

    S. Rosemberg, M. J. Telxelra, V. A. F. Alves, J. R. Perry… in Journal of Neuro-Oncology (1995)

  16. No Access

    Article

    Assessment of the experimental model of transplanted C6 glioblastoma in wistar rats

    Establishing in vivo glioblastoma models from cell lines requires a very strict methodology, in order to obtain reproducible tumors presenting all the characteristics of human spontaneous glioblastomas. In this r...

    F. San-Galli, P. Vrignaud, J. Robert, J.M. Coindre, F. Cohadon in Journal of Neuro-Oncology (1989)