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Article
PPARγ neddylation essential for adipogenesis is a potential target for treating obesity
The preadipocyte-to-adipocyte differentiation (adipogenesis) is a key process in fat mass increase and thus it is regarded as a compelling target for preventing or treating obesity. Of adipogenic hormone recep...
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Article
Open AccessRadiation-induced gamma-synuclein in regards to DC function
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Article
Open AccessModulation of dendritic cell function by the radiation-mediated secretory protein γ-synuclein
Recently, γ-synuclein (SNCG), which is also known as breast cancer-specific gene-1, has been demonstrated to be an adverse and aggressive marker in breast cancer. In our previous study, SNCG was significantly upr...
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Article
Open AccessWip1 suppresses apoptotic cell death through direct dephosphorylation of BAX in response to γ-radiation
Wild-type p53-induced phosphatase 1 (Wip1) is a p53-inducible serine/threonine phosphatase that switches off DNA damage checkpoint responses by the dephosphorylation of certain proteins (i.e. p38 mitogen-activ...
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Article
Identification of Kunitz trypsin inhibitor mutations using SNAP markers in soybean mutant lines
The Kunitz trypsin inhibitor (KTi) in soybean has several polymorphic types that are controlled by multiple alleles, which behave in a co-dominant fashion. Of these, Tia and Tib, which differ by nine amino aci...
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Article
N-acetylphytosphingosine-induced apoptosis of Jurkat cells is mediated by the conformational change in Bak
N-acetylphytosphingosine (NAPS), a sphingolipid derivative, is one of the well-known signal molecules that mediates various cellular functions, including cell growth, differentiation, and apoptosis. In this st...
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Article
Production of lithospermic acid B and rosmarinic acid in hairy root cultures of Salvia miltiorrhiza
Hairy root cultures of Salvia miltiorrhiza were established by infecting sterile plantlets with Agrobacterium rhizogenes ATCC 15834, and the transformation was proved by direct detection of the inserted T-DNA by ...
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Article
Electron Tomography of Mitochondria from Brown Adipocytes Reveals Crista Junctions
Electron microscope tomography was used to examine the membrane topology of brown adipose tissue (BAT) mitochondria prepared by cryofixation or chemical fixation techniques. These mitochondria contain an uncou...