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Abstract of the 68th Meeting (Spring Meeting) 6–9 March 1990, Heidelberg
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Open AccessIncreased doxorubicin uptake and toxicity in multicellular tumour spheroids treated with DC electrical fields
Electrochemotherapy (ECT) is a new approach to the treatment of tumours. In the present study, multicellular prostate tumour spheroids were treated with non-lethal direct current (DC) electrical fields, and up...
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35th Annual Meeting of the European Association for the Study of Diabetes
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Engineered embryonic stem cells for regnerative nedicine
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Open AccessFam40b is required for lineage commitment of murine embryonic stem cells
FAM40B (STRIP2) is a member of the striatin-interacting phosphatase and kinase (STRIPAK) complex that is involved in the regulation of various processes such as cell proliferation and differentiation. Its role...
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Erratum to: CaV2.3 E-/R-type voltage-gated calcium channels modulate sleep in mice
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Open AccessNeuronal developmental gene and miRNA signatures induced by histone deacetylase inhibitors in human embryonic stem cells
Human embryonic stem cells (hESCs) may be applied to develop human-relevant sensitive in vitro test systems for monitoring developmental toxicants. The aim of this study was to identify potential developmental to...
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Open AccessMedium-chain fatty acids modulate myocardial function via a cardiac odorant receptor
Several studies have demonstrated the expression of odorant receptors (OR) in various human tissues and their involvement in different physiological and pathophysiological processes. However, the functional ro...
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Open AccessCav2.3 R-type calcium channels: from its discovery to pathogenic de novo CACNA1E variants: a historical perspective
So-called pharmacoresistant (R-type) voltage-gated Ca2+ channels are structurally only partially characterized. Most of them are encoded by the CACNA1E gene and are expressed as different Cav2.3 splice variants (...