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Beyond reduction of atherosclerosis: PON2 provides apoptosis resistance and stabilizes tumor cells

Major contributors to atherosclerosis are oxidative damage and endoplasmic reticulum (ER) stress-induced apoptosis; both of which can be diminished by the anti-oxidative protein paraoxonase-2 (PON2). ER stress...

I Witte, S Altenhöfer, P Wilgenbus, J Amort, A M Clement, A Pautz… in Cell Death & Disease (2011)