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  1. Article

    Open Access

    Metformin modifies plasma microbial-derived extracellular vesicles in polycystic ovary syndrome with insulin resistance

    This study investigated changes in plasma microbial-derived extracellular vesicles (EVs) in patients with polycystic ovary syndrome and insulin resistance (PCOS-IR) before and after metformin treatment, and ai...

    Li** Hu, Guolin Hong, **gzhi Li, Mengkun Chen in Journal of Ovarian Research (2024)

  2. No Access

    Article

    Letter to the editor: “Definition of follicular helper T cell and cytokines expression in synovial fluid of rheumatoid arthritis”

    Guanru Chen, Huiying Chen, Zhuoyun Wang, He** Cai in Clinical Rheumatology (2024)

  3. No Access

    Article

    Comparison of the Measurement Properties of EQ-5D-5L and SF-6Dv2 in COVID-19 Patients in China

    There are limited studies comparing the health utility values of EQ-5D-5L and SF-6Dv2 within the same patient cohorts. The widespread transmission and recurring infections associated with Omicron variants amid...

    Ningxin Ding, Huixuan Zhou, Chen Chen in Applied Health Economics and Health Policy (2024)

  4. Article

    Open Access

    Exome sequencing and genome-wide association analyses unveils the genetic predisposition in hydroxychloroquine retinopathy

    To unveil the candidate susceptibility genes in chloroquine/hydroxychloroquine (CQ/HCQ) retinopathy using whole exome sequencing (WES) and genome-wide association study (GWAS).

    Hsun-I Chiu, Hui-Chen Cheng, Chih-Chiau Wu, Shih-Jen Chen, De-Kuang Hwang in Eye (2024)

  5. Article

    Open Access

    Gadolinium-enhanced intracranial aneurysm wall imaging and risk of aneurysm growth and rupture: a multicentre longitudinal cohort study

    In patients with an unruptured intracranial aneurysm, gadolinium enhancement of the aneurysm wall is associated with growth and rupture. However, most previous studies did not have a longitudinal design and di...

    Laura T. van der Kamp, Myriam Edjlali, Olivier Naggara in European Radiology (2024)

  6. No Access

    Article

    Molecular profile of bladder cancer progression to clinically aggressive subtypes

    Bladder cancer is a histologically and clinically heterogenous disease. Most bladder cancers are urothelial carcinomas, which frequently develop distinct histological subtypes. Several urothelial carcinoma his...

    Charles C. Guo, Sangkyou Lee, June G. Lee, Huiqin Chen in Nature Reviews Urology (2024)

  7. No Access

    Article

    Safety and effectiveness of the three-dimensional-printed guide plate-assisted rotation axis positioning of a hinged external fixator for the elbow

    We aimed to evaluate the safety and effectiveness of three-dimensional (3D)-printed guide plates for assisting in the positioning of the rotation axis of an elbow-hinged external fixator.

    Pengcheng Ma, Jiachun Zheng, Huizhi Chen, Weijie Yang in International Orthopaedics (2024)

  8. Article

    Open Access

    Role of arachidonic acid in ischemic heart disease under different comorbidities: risk or protection?

    In a translational study involving animal models and human subjects, Lv et al. demonstrate that arachidonic acid (AA) exhibits cardioprotective effects in diabetic myocardial ischemia, suggesting a departure f...

    Chengjia Li, Huijun Chen in Cardiovascular Diabetology (2024)

  9. No Access

    Article

    Regulations of m6A and other RNA modifications and their roles in cancer

    RNA modification is an essential component of the epitranscriptome, regulating RNA metabolism and cellular functions. Several types of RNA modifications have been identified to date; they include N6-methyladenosi...

    **n-Hui Chen, Kun-**ong Guo, **g Li, Shu-Hui Xu, Huifang Zhu in Frontiers of Medicine (2024)

  10. Article

    Open Access

    Differences in the depression and burnout networks between doctors and nurses: evidence from a network analysis

    Previous studies have demonstrated a strong association between depression and job burnout among healthcare professionals, but the results have been inconsistent, and there is a lack of in-depth exploration of...

    Zheng Zhang, Hui Chen, Xuting Li, Shurui Chen, Ziyu Wang, Jiaxin Yang in BMC Public Health (2024)

  11. Article

    Open Access

    Burden of drug use disorders in the United States from 1990 to 2021 and its projection until 2035: results from the GBD study

    Drug use disorders (DUDs) have emerged as one of the most significant public health crises, exerting a substantial influence on both community health and socio-economic progress. The United States (US) also su...

    Tongchao Zhang, Lin Sun, **aolin Yin, Hui Chen, Le** Yang in BMC Public Health (2024)

  12. Article

    Correction: Machine learning detects symptomatic patients with carotid plaques based on 6-type calcium configuration classification on CT angiography

    Francesco Pisu, Hui Chen, Bin Jiang, Guangming Zhu in European Radiology (2024)

  13. Article

    Open Access

    The performance of the practices associated with the occurrence of severe intraventricular hemorrhage in the very premature infants: data analysis from the Chinese neonatal network

    The occurrence of severe intraventricular hemorrhage (sIVH) was high in the very preterm infants (VPIs) in China. The management strategies significantly contributed to the occurrence of sIVH in VPIs. However,...

    Tiantian **ao, Liyuan Hu, Huiyao Chen, **nyue Gu, Jianguo Zhou in BMC Pediatrics (2024)

  14. Article

    Open Access

    Navel orange peel essential oil inhibits the growth and progression of triple negative breast cancer

    Triple Negative Breast Cancer (TNBC) is a particular type of breast cancer with the highest mortality rate. Essential oils are concerned more and more as potential anti-cancer drugs.

    Chao Yang, Wenwen Zhang, Shi **ang, Lai Chen in BMC Complementary Medicine and Therapies (2024)

  15. Article

    Open Access

    Notable dysthymia: evolving trends of major depressive disorders and dysthymia in China from 1990 to 2019, and projections until 2030

    Depressive disorders have been identified as a significant contributor to non-fatal health loss in China. Among the various subtypes of depressive disorders, dysthymia is gaining attention due to its similarit...

    Wei Wang, Yihe Wang, Feng Wang, Hui Chen, **aqing Qin, Lexia Yang in BMC Public Health (2024)

  16. Article

    Open Access

    The early career resilience experience of generation Z newly graduated registered nurses in standardized training in the emergency department: a qualitative study in Shanghai

    The period of standardized training is a transitional stage when Generation Z newly graduated registered nurses (Gen Z NGRNs) change their role from student to nurse. Affected by the COVID-19, they lack clinic...

    Peng Han, Yingying Sun, Huifeng Chen, Yue Liu, Shuyang Liu, **g Wang in BMC Nursing (2024)

  17. Article

    Open Access

    Non-pharmaceutical interventions in containing COVID-19 pandemic after the roll-out of coronavirus vaccines: a systematic review

    Non-pharmaceutical interventions (NPIs) have been widely utilised to control the COVID-19 pandemic. However, it is unclear what the optimal strategies are for implementing NPIs in the context of coronavirus va...

    **aona He, Huiting Chen, **nyu Zhu, Wei Gao in BMC Public Health (2024)

  18. Article

    Open Access

    Evaluation of the clinical application value of cytokine expression profiles in the differential diagnosis of prostate cancer

    The significance of tumor-secreted cytokines in tumor development has gained substantial attention. Nevertheless, the precise role of tumor-related inflammatory cytokines in prostate cancer (PCa) remains ambig...

    Rongfa Chen, Linna Liu, Hui Chen, Chao **ng in Cancer Immunology, Immunotherapy (2024)

  19. No Access

    Article

    Comparison of risk factors for OBL in FS-LASIK and SMILE correction for myopia and myopia astigmatism

    To find out the incidence and risk factors of opaque bubble layer (OBL) in eyes with myopia and myopic astigmatism following femtosecond laser–assisted in situ keratomileusis (FS-LASIK) and small incision lent...

    Zichen Wang, Mingrui Li, Haixia Ji, Hui Chen in Graefe's Archive for Clinical and Experime… (2024)

  20. Article

    Open Access

    Prenatal diagnosis of intrathoracic kidney and adrenal gland in left-sided congenital diaphragmatic hernia

    A 29-year-old primigravida at 31 weeks of gestation was referred for intrathoracic kidney (ITK). Ultrasound revealed left kidney intrathoracic placement with an anteriorly positioned ectopic adrenal gland. Mag...

    Tian Tian, Huizhu Chen, **g Tang, Hong Luo in Archives of Gynecology and Obstetrics (2024)

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