-
Article
Efficacy and Safety of Bufei Jiedu Granules in Treating Multidrug-Resistant Pulmonary Tuberculosis: A Multi-center, Double-Blinded and Randomized Controlled Trial
To assess the efficacy and safety of Bufei Jiedu (BFJD) ranules as adjuvant therapy for patients with multidrug-resistant pulmonary tuberculosis (MDR-PTB).
-
Article
Open AccessCorrection: Nomogram for predicting venous thromboembolism after spinal surgery
-
Article
A novel mutation in hERG gene associated with azithromycin-induced acquired long QT syndrome
Mutations in human ether-à-go-go-related gene (hERG) potassium channels are closely associated with long QT syndrome (LQTS). Previous studies have demonstrated that macrolide antibiotics increase the risk of c...
-
Article
Open AccessNomogram for predicting venous thromboembolism after spinal surgery
This study aimed to establish a nomogram to predict the risk of venous thromboembolism (VTE), identifying potential risk factors, and providing theoretical basis for prevention of VTE after spinal surgery.
-
Article
Open AccessOutcome and risk prediction of early progression in patients with extranodal natural killer/T cell lymphoma from the CLCG study
Recently, progression-free survival at 24 months (PFS24) was defined as clinically relevant for patients with extranodal NK/T cell lymphoma. Herein, the clinical data from two independent random cohorts (696 p...
-
Article
Phase transformation behavior of a dual-phase nanostructured Fe-Ni-B-Si-P-Nb metallic glass and its correlation with stress-impedance properties
A study of the phase transformation process of a Fe-Ni-B-Si-P-Nb metallic glass using a suite of advanced characterization tools is reported. Transmission electron microscopy (TEM) and small angle neutron scat...
-
Article
Administration of necrostatin-1 ameliorates glucocorticoid-induced osteonecrosis of the femoral head in rats
Glucocorticoid (GC)-induced osteonecrosis of the femoral head (ONFH) is a serious complication of glucocorticoid treatment and is characterized by dysfunctional bone reconstruction at necrotic sites. Our previ...
-
Article
Open AccessStreptococcus dysgalactiae subsp. dysgalactiae presents with progressive weakness in limbs: a case report and literature review
Streptococcus dysgalactiae subsp. dysgalactiae has been identified as an animal pathogen that is thought to occur only in animal populations. Between 2009 and 2022, humans infected with SDSD were reported rarely....
-
Article
New flexible CsPbBr3-based scintillator for X-ray tomography
The evolution of lead halide perovskites used for X-ray imaging scintillators has been facilitated by the development of solution-processable semiconductors characterized by large-area, flexible, fast photores...
-
Article
Treatment efficacy of HER2-mutant lung adenocarcinoma by immune checkpoint inhibitors: a multicenter retrospective study
Despite the remarkable clinical advance of immune checkpoint inhibitors (ICIs) in the treatment of lung cancer, there are limited studies focused on evaluating efficacy of ICIs for patients with human epiderma...
-
Article
Phase selection rule of high-entropy metallic glasses with different short-to-medium-range orders
When an equiatomic multi-component alloy is quenched from its molten state down to room temperature, either a solid solution crystalline alloy or a metallic glass is formed. The former is called a high-entropy...
-
Article
Bortezomib in combination with fludarabine plus cyclophosphamide for patients with relapsed or refractory mantle-cell lymphoma: results of the LYM-4003 study
This study aimed to identify the maximum-tolerated dose (MTD) of cyclophosphamide when combined with bortezomib and fludarabine (B-FC) in a phase 1b trial, and to assess the efficacy and safety of this combina...
-
Article
Cu(II) and Cd(II) removal from aqueous solution with LDH@GO-NH2 and LDH@GO-SH: kinetics and probable mechanism
Two novel adsorbents (LDH@GO-NH2 and LDH@GO-SH) were successfully synthesized by grafting thiol- or amino-functionalized GO onto LDH and their adsorption capacities for heavy metal ions (Cu(II) and Cd(II)) were s...
-
Article
PML Suppresses Influenza Virus Replication by Promoting FBXW7 Expression
Influenza A viruses (IAV) are responsible for seasonal flu epidemics, which can lead to high morbidity and mortality each year. Like other viruses, influenza virus can hijack host cellular machinery for its re...
-
Article
Multi-modality measurement and comprehensive analysis of hepatocellular carcinoma using synchrotron-based microscopy and spectroscopy
The visualization and data mining of tumor multidimensional information may play a major role in the analysis of the growth, metastasis, and microenvironmental changes of tumors while challenging traditional i...
-
Article
Correction to: Progression-free survival at 24 months and subsequent survival of patients with extranodal NK/T-cell lymphoma: a China Lymphoma Collaborative Group (CLCG) study
-
Article
Host-induced gene silencing of brown planthopper glutathione S-transferase gene enhances rice resistance to sap-sucking insect pests
Host-induced gene silencing (HIGS) of insect growth and development is a promising measure for pest control in practice; the feasibility of disarming insect detoxification of toxic phytochemicals via HIGS of i...
-
Article
Open AccessProgression-free survival at 24 months and subsequent survival of patients with extranodal NK/T-cell lymphoma: a China Lymphoma Collaborative Group (CLCG) study
Limited evidence supports the use of early endpoints to evaluate the success of initial treatment of extranodal NK/T-cell lymphoma (ENKTCL) in the modern era. We aim to analyze progression-free survival at 24 ...
-
Article
Open AccessGM-CSF mediates immune evasion via upregulation of PD-L1 expression in extranodal natural killer/T cell lymphoma
Granulocyte-macrophage colony stimulating factor (GM-CSF) is a cytokine that is used as an immunopotentiator for anti-tumor therapies in recent years. We found that some of the extranodal natural killer/T cell...
-
Article
Prior anti-PD-1 therapy as a risk factor for life-threatening peri-engraftment respiratory distress syndrome in patients undergoing autologous stem cell transplantation
Peri-engraftment respiratory distress syndrome (PERDS) is a kind of potentially life-threatening complication of autologous stem cell transplantation (ASCT). PERDS is characterized by fever, dyspnea, and hypox...