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Article
The effect of food on the pharmacokinetics of Sutetinib maleate capsule, an irreversible EGFR tyrosine kinase inhibitor, in healthy Chinese subjects
Sutetinib is an irreversible inhibitor of epidermal growth factor receptor (EGFR) and showed favorable efficacy and safety in patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) har...
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Article
Correction: Efficacy of Mesenchymal Stem Cell-Derived Extracellular Vesicles in the Animal Model of Female Reproductive Diseases: A Meta-Analysis
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Efficacy of Mesenchymal Stem Cell-Derived Extracellular Vesicles in the Animal Model of Female Reproductive Diseases: A Meta-Analysis
Female reproductive disorders, such as premature ovarian insufficiency (POI), intrauterine adhesion (IUA) or thin endometrium, and polycystic ovary syndrome (PCOS), are the main factors affecting fertility. Me...
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Article
Optimized HY via Thermal Modification as a Green Catalyst for One-Pot Synthesis of Fructose from Glucose Isomerization in Methanol/Water Medium
Glucose isomerization to fructose is a sustainable approach for the production of renewable chemicals from biomass derived carbohydrate and attracts increasing interest. In this work, HY was optimized by therm...
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Article
Open AccessInvolvement of impaired CD8+ mucosal-associated invariant T cells and myeloid-derived suppressor cells in polycystic ovary syndrome
Immune dysfunction is one of the mechanisms to promote polycystic ovary syndrome (PCOS). Various immune cells have been reported to be involved in the development of PCOS. Meanwhile, the disturbance of metabol...
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Article
Molecular Cloning and Characterization of FAD6 Gene from Chia (Salvia hispanica L.)
Plastidial Δ12 fatty acid desaturase (FAD6) is a key enzyme for linoleic acid (LA) and α-linolenic acid (ALA) biosynthesis. Chia (Salvia hispanica L.) is a revived omega-3 plant source that is richest in ALA leve...
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Article
Molecular cloning and characterization of two plastidial Δ12 fatty acid desaturase cDNAs from Perilla frutescens
The plastidial delta-12 fatty acid desaturase (FAD6) plays a key role in linoleic acid (LA) and α-linolenic acid (ALA) biosynthesis. Perilla (Perilla frutescens) is an important oilseed crop with the highest ALA ...
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Article
Patients with severe asthenoteratospermia carrying SPAG6 or RSPH3 mutations have a positive pregnancy outcome following intracytoplasmic sperm injection
To investigate the relation between mutations in ciliopathy-related SPAG6 and RSPH3 and male infertility with severe asthenoteratospermia characterized by multiple flagellar malformations and reveal the intracyto...
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Article
Open AccessCD4+/CD8+ mucosa-associated invariant T cells foster the development of endometriosis: a pilot study
Immune dysregulation is one of the mechanisms to promote endometriosis (EMS). Various T cell subpopulations have been reported to play different roles in the development of EMS. The mucosa-associated invariant...
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Article
Author Correction: Isolation and characterization of halotolerant phosphate-solubilizing microorganisms from saline soils
In the original article the acknowledgement section was incorrectly published
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Article
Isolation and characterization of halotolerant phosphate-solubilizing microorganisms from saline soils
Halotolerant phosphate-solubilizing microorganisms (PSMs) capable of producing plant-growth-promoting traits were grown on salt medium containing Ca3(PO4)2 or egg yolk. The number of colonies on plates with Ca3(P...
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Article
Genome-wide identification, systematic analysis and characterization of SRO family genes in maize (Zea mays L.)
SIMILAR TO RCD ONE (SRO) is a small plant-specific gene family, which play essential roles in plant growth and development as well as in abiotic stresses. However, the function of SROs in maize is still unknow...
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Article
Open AccessSpatial and temporal variations of nitrous oxide flux between coastal marsh and the atmosphere in the Yellow River estuary of China
To investigate the spatial and seasonal variations of nitrous oxide (N2O) fluxes and understand the key controlling factors, we explored N2O fluxes and environmental variables in high marsh (HM), middle marsh (MM...
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Article
Open AccessSeasonal and spatial variations of methane emissions from coastal marshes in the northern Yellow River estuary, China
To evaluate the seasonal and spatial variations of methane (CH4) emissions and understand the controlling factors, we measured CH4 fluxes and their environmental variables for the first time by a static chamber t...
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Open AccessPhosphorus biological cycle in the different Suaeda salsa marshes of the Yellow River estuary, China
Much uncertainty exists in the phosphorus (P) cycle in the marshes of the intertidal zone. This study explored the P cycling in the two Suaeda salsa marshes [middle S. salsa marsh (MSM) and low S. salsa marsh (LS...
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Article
Nitrogen biological cycle characteristics of seepweed (Suaeda salsa) wetland in intertidal zone of Huanghe (Yellow) River estuary
From April 2008 to November 2009, the nitrogen (N) cycle of plant-soil system in seepweed (Suaeda salsa) wetland in the intertidal zone of the Huanghe (Yellow) River estuary was studied. Results showed that soil ...
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Article
The complete genome sequence of a novel T4-like bacteriophage, IME08
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Open AccessHigh level soluble expression, one-step purification and characterization of HIV-1 p24 protein
P24 protein is the major core protein of HIV virus particle and has been suggested as a specific target for antiviral strategies. Recombinant p24 protein with natural antigenic activity would be useful for var...
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Open AccessSequence characteristics of T4-like bacteriophage IME08 genome termini revealed by high throughput sequencing
T4 phage is a model species that has contributed broadly to our understanding of molecular biology. T4 DNA replication and packaging share various mechanisms with human double-stranded DNA viruses such as herp...
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Application of stable isotope techniques in studies of carbon and nitrogen biogeochemical cycles of ecosystem
Stable isotope techniques have been proved useful as tools for studying the carbon (C) and nitrogen (N) biogeochemical cycles of ecosystem. This paper firstly introduced the basic principles and the distributi...