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  1. No Access

    Article

    ProPSA and the Prostate Health Index as predictive markers for aggressiveness in low-risk prostate cancer—results from an international multicenter study

    One of the major challenges in prostate cancer (PCa) treatment is distinguishing insignificant PCa from those forms that need active treatment. We evaluated the impact of PSA isoforms on risk stratification in...

    I Heidegger, H Klocker, R Pichler, A Pircher… in Prostate Cancer and Prostatic Diseases (2017)

  2. No Access

    Article

    [-2]proPSA is an early marker for prostate cancer aggressiveness

    The aim of the study was to evaluate the correlation between preoperative [-2]proPSA, the Gleason Score (GS) and the risk of non-organ-confined (NOC) disease in patients undergoing radical prostatectomy (RP).

    I Heidegger, H Klocker, E Steiner, V Skradski… in Prostate Cancer and Prostatic Diseases (2014)

  3. Article

    Open Access

    Distinct ERG rearrangement prevalence in prostate cancer: higher frequency in young age and in low PSA prostate cancer

    The TMPRSS2-ERG gene fusion resulting in ERG overexpression has been found in around 50% of prostate cancers (PCa) and is a very early event in tumorigenesis. Most studies have reported on selected surgical cohor...

    G Schaefer, J-M Mosquera, R Ramoner, K Park… in Prostate Cancer and Prostatic Diseases (2013)

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  4. No Access

    Article

    Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer

    Background: The type IV collagenases/gelatinases matrix metalloproteinase-2 (MMP-2) and -9 (MMP-9) play an important role in cancer invasion and metastasis. In the present study, we measured the expression of ...

    L Zhang, J Shi, J Feng, H Klocker, C Lee, J Zhang in Prostate Cancer and Prostatic Diseases (2004)

  5. No Access

    Article

    Amphiregulin is expressed in primary cultures of prostate myofibroblasts, fibroblasts, epithelial cells, and in prostate tissue

    The effect and expression of amphiregulin, a growth factor of the EGF-system was investigated in prostate primary cell cultures and in human prostate tissue. Amphiregulin increases proliferation in primary cul...

    N Tørring, BS Sørensen, ST Bösch, H Klocker… in Prostate Cancer and Prostatic Diseases (1998)