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  1. No Access

    Article

    New antitumor leads from a peptidomimetic library

    A parallel combinatorial library of over 1600 compounds has been designed and synthesized for the development of new potential peptidomimetic protein tyrosine kinase (PTK) inhibitor leads. These peptidomimetic...

    László Õrfi, Frigyes Wáczek, István Kövesdi, György Mészáros… in Letters in Peptide Science (1999)

  2. No Access

    Article

    New antitumor leads from a peptidomimetic library

    A parallel combinatorial library of over 1600 compounds has been designed and synthesized for the development of new potential peptidomimetic protein tyrosine kinase (PTK) inhibitor leads. These peptidomimetic...

    László Õrfi, Frigyes Wáczek, István Kövesdi, György Mészáros… in Letters in Peptide Science (1999)

  3. No Access

    Article

    Validation subset selections for extrapolation oriented QSPAR models

    One of the most important features of QSPAR models is their predictive ability. The predictive ability of QSPAR models should be checked by external validation. In this work we examined three different types o...

    Csaba Szántai-Kis, István Kövesdi, György Kéri, László Örfi in Molecular Diversity (2003)

  4. Article

    Open Access

    TT-232: An Anti-tumour and Anti-inflammatory Peptide Therapeutic in Clinical Development

    TT-232 is a structural derivative of the peptide hormone somatostatin with selective anti-proliferative and anti-inflammatory properties. It has a strong anti-tumour activity both in vitro and in vivo on a wide r...

    György Kéri, Richard Schwab… in International Journal of Peptide Research … (2005)

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  5. No Access

    Article

    Binding specificity of the l-arginine transport systems in mouse macrophages and human cells overexpressing the cationic amino acid transporter hCAT-1

    The uptake of l-arginine into mouse peritoneal macrophages can be inhibited by numerous amino acids and derivatives. Kinetic studies showed an almost entirely competitive inhibition for both cationic and neutral ...

    Dániel Erős, László Őrfi, Ildikó Csuka, György Kéri, András Hrabák in Amino Acids (2009)

  6. No Access

    Article

    Proteomics strategy for quantitative protein interaction profiling in cell extracts

    Quantitative information is necessary to determine which protein interactions are the most relevant in a cellular context. A defined set of affinity purification experiments combined with quantitative mass spe...

    Kirti Sharma, Christoph Weber, Michaela Bairlein, Zoltán Greff… in Nature Methods (2009)